Dermatological Alterations Induced by Gynecological Hormonal Imbalances: Acne, Hirsutism, and Alopecia
October 2025
in “
Zenodo (CERN European Organization for Nuclear Research)
”
Studysummary This review describes how sex hormones like estrogens and androgens influence skin health, linking hormonal fluctuations to conditions such as acne and hair loss, and underscores the importance of a multidisciplinary approach to treatment that includes mental health support. Our plain-language summary of this paper — not a Tressless recommendation.
Hormonal imbalances, particularly involving androgens, significantly impact dermatological conditions such as acne, hirsutism, and alopecia. Conditions like polycystic ovary syndrome, characterized by androgen excess and insulin resistance, exacerbate these skin issues. Hormonal acne, often found in the lower facial region, can be treated with hormonal contraceptives, antiandrogens, or isotretinoin. Hirsutism is assessed with scoring systems and managed with hormonal and cosmetic treatments. Hormonal hair loss, including female pattern thinning and telogen effluvium, is linked to estrogen withdrawal or thyroid issues, requiring trichoscopy and hormonal profiling for diagnosis. A multidisciplinary approach involving dermatological, gynecological, and endocrine care, along with mental health support, is crucial for improving outcomes.
