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This study found that finasteride decreases melanin levels in melanocyte and melanoma cells by inhibiting MC1R, without causing cytotoxicity, suggesting its potential role in regulating melanogenesis.

This study describes vitiligo as an autoimmune disease marked by depigmented skin and mucosal patches, and reviews its complex pathogenesis and diagnostic features. Treatment aims for disease control and repigmentation through various topical and systemic therapies, phototherapy, and surgical options, emphasizing personalized, multimodal approaches.

This article reviews several benign skin conditions in newborns, emphasizing the importance of correct identification to prevent unnecessary concern and interventions, but reports no new clinical results.

This study found that patients with frontal fibrosing alopecia had lower epidermal melanocyte counts and reduced epidermal thickness compared to lichen planopilaris patients and controls, suggesting a link with hypopigmentation.

This article highlights the potential of reflectance confocal microscopy for diagnosing and monitoring melasma treatments, and discusses new therapies using oral melatonin, glutathione, and resveratrol, as well as the growing interest in oral minoxidil for alopecia.

This study found that treating a 3D hair dermal papilla model with rice bran extract and electromagnetic fields increased melanogenesis, suggesting potential for vitiligo and white hair therapies.

In this case report, a 17-year-old male on sodium valproate therapy developed rare longitudinal melanonychia, suggesting sodium valproate can induce nail pigmentation as a side effect.

This case report describes canities subita, characterized by sudden hair whitening without hair loss, in a patient following a stressful event, suggesting an immune system involvement.

This study concluded that pseudopelade is an autosomal dominant condition, distinct from other forms of alopecia, characterized by atrophic hair follicle loss and notable familial association.

This article reviews the early establishment of dermatology as a specialty in the U.S. and documents the initial descriptive errors in understanding Darier's disease, offering no new clinical data.

This review discusses genetically-engineered mouse models for studying melanocytes and reports no new experimental findings; it emphasizes their potential to address unanswered questions in melanoma biology.

In this study, α-MSH and cyclic AMP were found to stimulate melanogenesis in hair follicle cultures, while cyclic GMP and melatonin inhibited melanin production but not tyrosinase activity.

This study observed two cases of pigmented epithelioid melanocytoma suggesting potential differing origins: one from a hair follicle's outer root sheath and another from an intradermal nevus.

In this study, adrenalectomy in black rats on a vitamin B-deficient diet restored hair growth and melanin deposition, effects reversed using adrenal cortical hormones.

This report found follicular red dots in patients with scalp pigmentary disorders, suggesting they might be linked to the scalp's vascular structure and may have implications for conditions like discoid lupus erythematosus.

This case report presents the first documented instance in India of cutaneous amyloidosis causing pigmented papules on the ear pinna, with lesions resolving after treatment with topical tretinoin.

This study demonstrates that extracellular ATP induced by UV radiation promotes melanin production in human melanocytes, suggesting ATP-induced purinergic signaling may influence skin pigmentation.

An 86-year-old man had a rare tongue melanoma but refused treatment, showing the need for early cancer detection and treatment.

This compilation reviews multiple dermatologic studies, reporting findings such as the lack of a psoriasis-susceptibility allele in cluster 17, and highlighting a mouse model for studying hair follicle formation, among others.

This study found that DNA hypermethylation was present in melasma lesions, and treatments with sunscreen, niacinamide, and retinoic acid were associated with decreased methylation and clinical improvement.

In this study using genetic mouse models, researchers discovered that senescent melanocytes in nevi secrete osteopontin, which activates hair stem cells, enhancing hair growth; this process is mirrored in human hairy nevi, suggesting a potential therapeutic target for regenerative disorders.

A woman with severe hair loss regrew mostly white hair after treatment.

This study found that dermoscopy showed distinctive patterns for different types of alopecia, supporting its clinical usefulness for diagnosing diseases with small round or oval hairless patches on the scalp.

This report describes a case of trichostasis spinulosa, a condition with pruritic, black papules on the face caused by keratotic plugs with embedded vellus hairs.

This study describes how feather pigmentation in birds is regulated by melanocyte distribution, differentiation, and patterned agouti expression, contributing to diverse and adaptive color patterns.

In this study, researchers examined chicken feather follicle tissues from differently colored chickens and found that the genes SLC45A2 and GPNMB are involved in promoting melanin deposition, which enriches understanding of the genetic mechanisms affecting feather color.

This study found that direct interactions between human dermal papilla cells and melanocytes under low oxygen conditions improved cell functions and could be important for hair regeneration efforts.