Commentary: Darier-White Disease

    January 1983 in “ Archives of dermatology ”
    Rhonda Rand
    TLDR The conclusion is that Darier-White disease was accurately described by White but he missed the key feature of dyskeratotic cells which Darier identified.
    In 1889, James C. White and Ferdinand Jean Darier independently described a skin condition now known as Darier-White disease. White's clinical description was detailed but missed identifying dyskeratotic cells, the key histopathologic feature of the disorder, and incorrectly suggested that hair follicles were primarily affected. Darier correctly identified the dyskeratotic regions in the epidermis. This condition, also referred to as keratosis follicularis or psorospermose folliculaire végétante, became recognized as a distinct dermatological entity.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 550 results

      community 24M still losing on Dut and Oral Min

      in Update  26 upvotes 5 months ago
      A 24-year-old male is losing hair despite using dutasteride and oral minoxidil, with no regrowth from April to October 2024. He is considering increasing his dosage and looking for cheaper prescriptions, while others recommend consulting a trichologist or trying different treatments.

      community Fighting Hair loss AND Grey Hair

      in Treatment  18 upvotes 2 years ago
      The user is treating hair loss with topical Minoxidil, Finasteride, RU58841, microneedling, and Ketoconazole. For grey hair, they use L-Cysteine, L-Methionine, and PABA, and have noticed some re-pigmentation.

      community Does finasteride/dutasteride reverse aging?

      in Chat  45 upvotes 5 months ago
      Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

      community Copper Literally Saved My Life (and My Baldness)

      in Treatment  11 upvotes 1 month ago
      Oral copper supplementation significantly improved hair regrowth for someone who experienced severe hair loss after stopping minoxidil, suggesting copper deficiency might hinder minoxidil's effectiveness. The user now only takes copper and occasionally uses microneedling, recommending others to try copper if minoxidil alone isn't effective.

    Similar Research

    5 / 1000+ results