DNA Methyltransferases in Malar Melasma and Their Modification by Sunscreen with 4% Niacinamide, 0.05% Retinoic Acid, or Placebo

    April 2019 in “ BioMed Research International ”
    Andrés Eduardo Campuzano-García, Bertha Torres‐Álvarez, Diana Hernández‐Blanco … Juan Pablo Castanedo-Cázares
    Studysummary This study found that DNA hypermethylation was present in melasma lesions, and treatments with sunscreen, niacinamide, and retinoic acid were associated with decreased methylation and clinical improvement.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on downloads.hindawi.com →
    Discuss this study in the Community →

    Research cited in this study 2

    1. Topical Niacinamide 4% and Desonide 0.05% for Treatment of Axillary Hyperpigmentation: A Randomized, Double-Blind, Placebo-Controlled Study Clinical Cosmetic and Investigational Dermatology · 2013
    2. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011