57 citations,
April 2009 in “Differentiation” SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
[object Object] 55 citations,
December 2014 in “Dermatologica sinica/Zhōnghuá pífūkē yīxué zázhì” Keratinocytes control how melanocytes work.
46 citations,
April 2014 in “PLOS ONE” Gray hair may be caused by lower antioxidant activity in hair cells.
45 citations,
April 2016 in “Journal of Dermatological Science” The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
43 citations,
October 2005 in “Molecular and cellular endocrinology” Hair melanocytes help the skin respond to stress and regulate hair pigmentation.
40 citations,
November 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Different melanocyte types in hair follicles either survive or die during the catagen phase.
39 citations,
March 2017 in “Dermatologic clinics” UV light can help stimulate the growth of new pigment cells from hair follicles in people with vitiligo.
34 citations,
December 1988 in “Pigment Cell Research” Melanocytes appear in fetal skin early, but their development details are still unclear.
30 citations,
April 2013 in “Journal of Investigative Dermatology” Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.
[object Object] 26 citations,
February 2022 in “Journal of pineal research” Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.
24 citations,
September 2008 in “Clinical and experimental dermatology” Repigmentation in vitiligo may come from melanocyte stem cells in the skin.
17 citations,
December 2013 in “Dermatologic Surgery” The treatment improved hair color in most vitiligo patients without major side effects.
16 citations,
October 2004 in “Journal of Investigative Dermatology” Normal human melanocytes can avoid cell death through multiple pathways.
14 citations,
October 2020 in “Scientific reports” Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.
14 citations,
November 2013 in “PloS one” HGF/SF increases skin melanocytes but doesn't change melanin type or amount.
14 citations,
April 2005 in “Experimental Dermatology” Stressed fibroblasts greatly increase melanin production in hair, skin, and eye cells, mainly due to a growth factor called bFGF.
11 citations,
February 2018 in “Archives of Pharmacal Research” Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.
10 citations,
June 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D receptor helps protect skin cells from UV damage and supports their growth.
10 citations,
May 2016 in “Journal of Dermatological Science” PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.
10 citations,
November 2010 in “Pigment Cell & Melanoma Research” Only skin melanocytes, not other types, can color hair in mice.
8 citations,
January 2017 in “Stem Cells International” A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
8 citations,
August 2015 in “Journal of dermatological science” Rhododendrol in skin-whitening products can cause skin depigmentation and immune reactions.
7 citations,
June 2021 in “Cell Proliferation” Low oxygen levels improve the function of hair and skin cells when they are in direct contact.
6 citations,
October 2018 in “Bioelectromagnetics” Rice bran extract and low-frequency electromagnetic fields together may help treat vitiligo and white hair.
6 citations,
January 2018 in “International Journal of Dermatology” Repigmentation patterns in vitiligo depend on melanocyte source, lesion status, and therapy choice.
5 citations,
August 2012 in “Archives of Dermatology” The immune system can cause permanent skin and hair whitening by attacking pigment cells.
3 citations,
November 2022 in “Experimental dermatology” Melatonin may inhibit melanoma growth and has potential as a cancer therapy aid, but its effects on human skin pigmentation need more research.
2 citations,
June 2013 in “In Vitro Cellular & Developmental Biology - Animal” Melanocytes from human fetal hair follicles were successfully cultured, showing potential for hair disease research and clinical use.
1 citations,
September 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing Dicer from pigment cells in newborn mice causes early hair graying and changes in cell migration molecules.
1 citations,
November 2022 in “International journal of trichology” A woman's premature gray hair turned mostly black again after using Greyverse solution and hair supplements for 5 months.