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WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Fibrinogen/LDL apheresis may improve speech perception in sudden hearing loss, especially for those with high fibrinogen and LDL levels.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

High androgen levels in young women with PCOS are linked to higher blood pressure.

Myrtle has various health benefits and potential for medicine development.

Zinc is effective for treating various skin conditions, including warts and acne.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Telocytes might help with skin repair and regeneration.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Follicular Unit Extraction (FUE) is a less invasive hair transplant method with minimal scarring, suitable for about 60% of patients, especially those needing fewer grafts and quicker recovery.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Humans lost body hair relatively recently in evolution.

Estrogen therapy can reduce skin aging but has cancer risks.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Most people with systemic lupus erythematosus have skin problems, and skin symptoms are often the first sign of the disease.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Alopecia areata is a common autoimmune disease affecting about 2% of people, causing significant disability and often associated with mental health issues and other autoimmune conditions.