research Treatment of Severe Alopecia Areata with the Oral Janus Kinase Inhibitor, Tofacitinib: A Retrospective Chart Review
Tofacitinib may help regrow hair in severe alopecia areata, but results differ greatly between people.
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research Pegylated Liposomal Doxorubicin in the Treatment of Breast Cancer
PLD is an effective and safer alternative for treating breast cancer.
research Small Cell Lung Cancer: Results of a Phase II Study of 1,2,4-Triglycidylurazol
The drug TGU was ineffective against small cell lung cancer and caused significant bone marrow suppression.
research Limited Stage Small Cell Lung Cancer: Treatment Strategies and Prognostic Factors
Treat limited stage small cell lung cancer with chemotherapy and radiation, and consider preventive brain radiation for better survival chances.
research Hair Removal in Hirsute Women with Normal Testosterone Levels: A Randomized Controlled Trial of Long-Pulsed Diode Laser vs. Intense Pulsed Light
Both intense pulsed light and long-pulsed diode laser effectively reduced facial hair in women, with no significant difference in satisfaction after 6 months, but intense pulsed light was more painful.
research 5α-Reductase Inhibitor Therapy: Should Physicians Be Concerned With Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients?
Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.
research Total Prostate Volume as Risk Factor for Semen Pathologies in Aging Male
Larger prostate size in older men may be linked to poorer semen quality and fertility issues.
research Androgen Receptor Genetic Variant Predicts COVID-19 Disease Severity: A Prospective Longitudinal Study of Hospitalized COVID-19 Male Patients
A certain genetic variant in the androgen receptor may predict the severity of COVID-19 in men.
research Lichen Planopilaris With Foreign-Body Granuloma
Foreign-body granuloma may be a marker for late-stage Lichen Planopilaris and should be considered in diagnosis.
research Human Exposure to Heavy Metals Over the Last 100 Years
People today have lower levels of arsenic, lead, cadmium, and iron in their hair than people did 100 years ago.
research Pharmacokinetics, Toxicity, and Activity of Intravenous Dextran Sulfate in Human Immunodeficiency Virus Infection
Dextran sulfate was found to be toxic and ineffective for treating HIV.
research Cyclin-Dependent Kinase 4/6 Inhibitors and Dermatologic Adverse Events: Results from the EADV Task Force Dermatology for Cancer Patients International Study
Skin side effects from CDK4/6 inhibitors in breast cancer patients are generally mild and treatable, allowing most patients to continue treatment.
research P62 Pre-Clinical Pharmacological and Skin Penetration Profile of LDE255, a Novel and Specific Smoothened Antagonist
LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.
research Detection of Membrane Androgen-Binding Site in Living Rat Prostate and Evaluation of Its Role in Prostate Blood Flow Regulation
The research found that androgens help control blood flow in the rat prostate through a specific binding site.
research Low Dose Oral Minoxidil in COVID-19-Associated Telogen Effluvium: A Retrospective Analysis of 69 Patients
Low-dose oral minoxidil helps hair regrowth in COVID-19-related hair loss with few side effects.
research Management of Cutaneous and Extracutaneous Side Effects of Smoothened Inhibitor Therapy for Advanced Basal Cell Carcinoma
The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.
research Management of Hair Loss After Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Insight Into the Pathophysiology With Implication for Better Management
Hair loss is a frequent long-term effect of COVID-19, and oral minoxidil is the most common effective treatment.
research Folliculitis Decalvans: A Multicenter Review of 82 Patients
Oral clindamycin and rifampicin are the most effective treatments for Folliculitis decalvans.
research Lichen Planus Pigmentosus and Lichen Planus Pigmentosus: 35 Cases in Armenia, Colombia
Lichen planus pigmentosus and fibrosing frontal alopecia in Colombia are likely different stages of the same disease.
research Dermatoscopic Analysis of Pseudocyst of the Scalp
Both azathioprine and betamethasone treatments help with hair regrowth in alopecia areata, but azathioprine may have fewer side effects.
research Factors Associated With Traction Alopecia in Women Living in Yaoundé, Cameroon
Older age and specific haircare practices increase the risk of traction alopecia, and education on these factors could help prevent it.
research How Do 5-Alpha-Reductase Inhibitors Change PSA Density in Patients on Active Surveillance?
5-alpha-reductase inhibitors lower PSA density but higher PSA density indicates disease progression.
research Postoperative Radiotherapy for Cutaneous Squamous Cell Carcinoma in Patients With Microscopic Residual Disease
Radiotherapy is a good option when further surgery for skin cancer isn't preferred, but more research is needed to compare it with other methods.
research Effect of Topical Liquid Nitrogen on Pain Reduction During Intradermal Platelet-Rich Plasma Therapy in Scalp for Androgenic Alopecia
Topical liquid nitrogen reduces pain during PRP therapy but doesn't affect patient satisfaction.
research Docetaxel, Cisplatin and 5-Fluorouracil in Patients with Locally Advanced Unresectable Head and Neck Cancer: A Phase I-II Feasibility Study
The treatment combining docetaxel, cisplatin, and 5-FU is feasible and effective for advanced head and neck cancer.
research Is SFRP-4 an Early Potential Biomarker Related to Diabetes and Hypertension in Patients with Androgenic Alopecia?
SFRP-4 might be an early indicator of diabetes and hypertension in men with androgenic alopecia.
research Role of Vitamin D Supplementation Therapy on Ovulation and Insulin Resistance in Women with PCOS: A Randomized Controlled Trial
Vitamin D supplements increased ovulation rates in women with PCOS who were vitamin D deficient.
research Madarosis: A Qualitative Study to Assess Perceptions and Experience of Australian Patients with Early Breast Cancer Treated with Taxane-Based Chemotherapy
Madarosis (eyebrow and eyelash loss) significantly affects quality of life for breast cancer patients on taxane-based chemotherapy.
research Trichology to Predict Efficacy of Scalp Cooling: New Pathologic Insights Besides Encouraging Clinical Results
Scalp cooling can effectively prevent hair loss during chemotherapy, improving patients' quality of life.
research Low-Dose Oral Minoxidil for Female Pattern Hair Loss: A Unicenter Descriptive Study of 148 Women
Low-dose oral minoxidil effectively treats female hair loss with good safety.