44 citations
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August 1996 in “Drugs & Aging” Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.
January 2024 in “Current research in toxicology” This review reports that thallium poisoning causes severe neurological damage, with early gastrointestinal symptoms and later neurological dysfunction, and highlights the importance of early diagnosis and Prussian blue as an effective antidote.
48 citations
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January 2008 in “European Neurology” This study demonstrated that acute thallium poisoning primarily manifests with gastrointestinal issues, polyneuropathy, and dermatological changes, and treatments like hemoperfusion and hemodialysis may improve symptoms.
60 citations
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February 2003 in “Postgraduate Medical Journal” In this report, it was noted that severe paresthesia, ophthalmoplegia, cerebellar and extrapyramidal signs, and alopecia can strongly indicate thallium poisoning, and haemodialysis may be beneficial even in the third week after poisoning.
1 citations
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October 2010 in “Series in cosmetic and laser therapy” Mesotherapy is a minimally invasive treatment with potential benefits and risks, requiring standardized practices and further investigation.
April 2016 in “Journal of Investigative Dermatology” This study identified mefloquine as a potent inducer of lethal ER stress that effectively eliminated vemurafenib-resistant and sensitive melanoma cells, suggesting its potential for repurposing as a melanoma treatment.
3 citations
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May 1963 in “Radiology” This article reports on five cases of thallium poisoning seen at Hospital Dos de Mayo, Lima, Peru, highlighting the clinical symptoms and diagnostic features observed, including a case confirmed through various laboratory tests.
33 citations
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January 2009 in “Contraception” This review summarizes the use of chlormadinone acetate for hormone replacement therapy and contraception, highlighting its anti-androgenic effects, contraceptive efficacy, and clinical tolerability, without offering new clinical results.
April 2023 in “Journal of Investigative Dermatology” This study found that ALRN-6924 effectively protected human hair follicles from cyclophosphamide-induced damage in an ex vivo setting, suggesting it may reduce both acute and permanent chemotherapy-induced alopecia.
14 citations
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January 2017 in “Annals of Dermatology” In this retrospective study, low-dose methotrexate was observed to be effective and well-tolerated in treating recalcitrant alopecia areata multiplex, achieving complete or near-complete hair regrowth in about 90% of patients despite some experiencing elevated liver enzymes and gastrointestinal discomfort.
5 citations
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June 2015 in “Journal of dermatology” This letter to the editor describes a case of anagen effluvium due to thallium poisoning from Chinese herbal medicine and rodenticide but reports no new research findings.
June 2007 in “Emergency medicine news” This article discusses the symptoms, diagnosis, and treatment of thallium poisoning, with no new clinical results reported; the authors emphasize the importance of early suspicion for effective intervention.
23 citations
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June 1950 in “American journal of diseases of children” This article discusses the interest in folic acid antagonists for leukemia treatment, noting their potential mechanism of interfering with cellular growth, but reports no new clinical results.
May 2024 in “Journal of biomaterials science. Polymer ed.” This study found that three-layer dissolving microneedles for delivering Minoxidil showed improved skin drug penetration and reduced irritation risk compared to traditional Minoxidil cream, suggesting a promising alternative for alopecia areata treatment.
3 citations
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September 1980 in “Experientia” In this study, the pharmacological action of dobutamine on rabbit retinae was found to be distinct from that of other dopamine analogs like apomorphine and N-methyl-dopamine.
1 citations
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January 2004 in “Drugs” Ethinylestradiol/Chlormadinone Acetate is a safe and effective birth control pill that also helps regulate menstrual cycles, reduces period pain, and treats certain skin and hair conditions.
This study found that Dex-loaded hyaluronic acid hydrogel microneedles significantly reduced pain in an acute inflammatory visceral pain model without sedation, suggesting a promising and patient-friendly alternative to intravenous delivery.
119 citations
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June 1993 in “BMJ” This article discusses the high toxicity and potential use of thallium as a poison, highlighted by two cases of intentional thallium poisoning.
January 2015 in “Indo American Journal of Pharmaceutical Research” This article describes mesotherapy, a technique involving small doses of compounds injected into the skin for cosmetic uses like aging skin and fat reduction, and provides no new clinical results.
January 2023 in “Indian Journal of Forensic and Community Medicine” This report describes two cases of thallium poisoning with gastrointestinal symptoms, peripheral neuropathy, and alopecia, which were effectively treated using activated charcoal, potassium chloride, and hemodialysis.
October 2025 in “Frontiers in Endocrinology” This study confirmed that methimazole use is associated with agranulocytosis, pyrexia, exposure during pregnancy, and hyperthyroidism, while also identifying new safety signals like premature birth and septic shock that require further investigation.
This study found that mycophenolate mofetil was well tolerated and effective as a second-line treatment for autoimmune hepatitis in patients who were intolerant to azathioprine.
July 2026 in “Dermatology Practical & Conceptual” This study found that while both microneedling-assisted methotrexate and triamcinolone acetonide treatments led to improvements in recalcitrant alopecia areata, methotrexate-treated areas had significantly better outcomes in terms of SALT score reduction, patient satisfaction, and relapse rates, suggesting its superior short-term efficacy.
January 2016 in “Reactions Weekly” A girl's hair loss from a pharmacy error improved after getting the right medicine.
4 citations
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September 2011 in “American Journal of Clinical Dermatology” This case series suggests that EE/CMA 0.03mg/2mg may help manage dermatological disorders related to androgen excess, as evidenced by symptomatic improvements in the four patients treated.
1 citations
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May 2007 in “Emergency medicine news” This article discusses thallium poisoning and its diagnosis, symptoms, and treatment options, emphasizing the need for awareness due to its misleading symptoms and potential for misdiagnosis.
January 2010 in “Guoji yaoxue yanjiu zazhi” This review discusses thallium poisoning, its mechanisms, clinical symptoms, and treatment approaches, highlighting hemoperfusion as an effective method to eliminate absorbed thallium, though no new clinical results are presented.
3 citations
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April 2011 in “Expert Review of Dermatology” This review discusses the use of mesotherapy, highlighting its popularity and the lack of large, randomized controlled trials, and advises cautious use.
January 2023 in “National journal of physiology, pharmacy and pharmacology” This study of South Indian patients with autoimmune rheumatic diseases using low-dose methotrexate reported that while mild adverse effects such as hair loss and nausea were common, serious events like cytopenia were less frequent, and folic acid supplementation significantly reduced their prevalence.
April 2024 in “Authorea (Authorea)” This case report describes a patient with chronic renal failure on hemodialysis who experienced hair depigmentation while taking heptaminol, with the condition reversing after discontinuing the medication; the exact mechanism causing the color change is still unclear.