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This study examined the effects of constant-release melatonin on the SOX21 gene in Inner Mongolia Cashmere goats, finding that it stabilized gene expression and reduced stress responses with notable expression changes except in March, April, and May.

This review article highlights that mesotherapy, a popular non-surgical procedure in aesthetic dermatology, involves injecting a mixture of compounds into the skin for purposes like skin rejuvenation and hair loss treatment, but lacks large-scale studies on its efficacy and safety.

This study found that boosting the synthesis of neural-derived 17β-estradiol effectively counteracted the impairment of hippocampal long-term potentiation caused by amyloid beta 1-42 in rat hippocampal slices, with the effect seemingly linked to glutamate NMDAR signaling.

Minoxidil base is preferred for hair loss treatment, but minoxidil sulfate may be an alternative for unresponsive patients.

This study reports that Hair RiseTM microemulsion, made from plant extracts, significantly enhanced hair follicle cell growth and improved hair growth signaling pathways, suggesting it as a plant-based alternative for androgenetic alopecia treatment.

New mutations in hair keratin genes cause the rare hair disorder monilethrix.

In this study, researchers explored whether minoxidil, a common treatment for androgenetic alopecia, may have estrogenic activity and found preliminary evidence suggesting it could act as a partial agonist of Estrogen Receptor α (ERα).

This article presents five family cases of monilethrix and reports that neither vitamins nor desquamative ointments are effective treatments, although symptoms may spontaneously regress over time.

This abstract describes monilethrix, an autosomal dominant genodermatosis with symptoms like hair fragility and keratosis pilaris, and does not report new experimental results.

This study found that early diagnosis using gas chromatography/mass spectrometry and appropriate long-term treatment are crucial for improving outcomes in patients with methylmalonic acidemia.

This study investigated how the antioxidant MitoQ and the enzyme CYP19A1 influence mitochondrial function in androgenetic alopecia. In a mouse model, both CYP19A1 overexpression and MitoQ treatment improved mitochondrial health and reversed DHT-induced hair loss factors, suggesting potential therapeutic targets for this condition.

This study found that mu-crystallin gene expression in mouse skin is highest during the anagen phase of hair development, suggesting its possible role in hair follicle growth.

In this study, researchers found that minoxidil sulfate enhances the anti-inflammatory effects of the JAK inhibitor baricitinib in alopecia areata, modulating inflammatory signals and preserving immune privilege features in human hair cells, which suggests potential benefits for combined therapy.

This study found that Minoxidil included in triamino alpha-cyclodextrin significantly promoted hair growth in mice, potentially due to its enhanced substantivity on skin.

This study found that overexpression of an enzyme in transgenic mice led to distorted polyamine levels, resulting in permanent hair loss and female infertility.

Mycophenolic acid may help hair grow by activating pathways important for hair growth.

This study reports that hair regeneration can be stimulated by small molecules like α-ketoglutarate, α-ketobutyrate, rapamycin, and metformin, which activate autophagy pathways.

This study found that a dietary supplement containing L-cystine, medicinal yeast, and pantothenic acid significantly improved hair growth in women with telogen effluvium over six months compared to placebo.

This study reported that atelocollagen enhances collagen synthesis and reduces oxidative stress in aged skin by increasing glycine uptake through GlyT1, resulting in improved skin elasticity and collagen density in aged mice, with effects superior to glycine alone.

This study found that using an ultrasound hollow microneedle array enhanced transdermal delivery of finasteride, accelerating hair regrowth in mice with androgenetic alopecia compared to other delivery methods.

This study found that methyl jasmonate can induce tanshinone biosynthesis in S. miltiorrhiza by affecting the expression of the SmMEC gene, as supported by RT-PCR and transcriptomic data.

This study discusses a potential new treatment called AMPLEX PLUS that may significantly slow hair loss and stimulate new hair growth by influencing the transition of hair follicles from the telogen phase to the active anagen phase.

This laboratory study found that collagen matrices with high-sulfated hyaluronan may enhance the cultivation of human keratinocytes and melanocytes from hair follicles for epidermal graft development.

In this narrative review, researchers found that biomimetic peptides, which mimic natural biological functions, show potential in improving hair density and thickness in people with alopecia, although more robust clinical studies are needed to confirm their efficacy for clinical use.

This study reported that certain minoxidil conjugates, specifically those with spermine, methylenedianiline, and diaminofluorene, were able to induce differentiation in HL-60 acute myeloid leukemia cells without toxicity at a concentration of 10 μM.

This study found that spermidine, a polyamine, plays an essential role in hair growth in sheep follicles, while spermine is not required for normal follicle function.

This study found that a combination of oral compounds improved metabolic activity, cell viability, and proliferation in hair follicular keratinocytes, with L-cystine playing a key role in protection against oxidative stress.

This study found that ethosome-loaded minoxidil and tocopherol acetate improved hair regeneration and regulated the microenvironment around hair follicles better than commercial minoxidil in androgenic alopecia model mice, showing promise as a treatment strategy.