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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

Removing part of the vitamin D receptor stops vitamin D from working properly.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Different types of skin cells play specific roles in development, healing, and cancer.

Targeted cancer therapies often cause serious skin problems that need careful management.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Some medicinal plants can help heal wounds and may lead to new treatments.

Stem cell niches support, regulate, and coordinate stem cell functions.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Estrogen therapy can reduce skin aging but has cancer risks.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Aging causes skin stem cells to work less effectively.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.