August 2025 in “International Journal of Molecular Sciences” This study found that compounds isolated from Osmanthus fragrans var. aurantiacus demonstrated antioxidative and anti-inflammatory activities, potentially offering therapeutic benefits for inflammatory bowel diseases by inhibiting COX-2 and iNOS enzymes and blocking ERK 1/2 MAPK signaling.
June 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” The researchers reported that basement membrane heterogeneity, especially laminin α5 composition, plays a critical role in distinct inter-tissue interactions and hair cycle regulation in mouse hair follicles.
This study found that some white or grey hairs can naturally regain pigmentation, suggesting hair greying may be reversible in certain conditions linked to psychological stress.
April 2020 in “International Journal of Cosmetic Science” This study found that improved protein extraction methods enhanced the resolution of hair proteins on gels, but differences in protein abundance between curly and straight Japanese women’s hair were minimal and unlikely to affect hair structure.
May 2015 in “Journal of Dermatological Science” Researchers found a new area on chromosome 2 linked to a genetic hair loss condition.
62 citations
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March 2008 in “American Journal of Human Genetics” This study located a potential genetic link for androgenetic alopecia on chromosome 3q26, marking an early step in identifying new susceptibility genes for male pattern baldness.
29 citations
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March 2000 in “Journal of Investigative Dermatology” The gene for Marie Unna hereditary hypotrichosis is located on chromosome 8p21.
26 citations
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May 2024 in “Molecular Neurodegeneration” This review assesses existing knowledge about the 17q21.31 inversion polymorphism, highlighting its genetic structure differences across ancestries, associations with various diseases, and implications for precision medicine and drug discovery.
9 citations
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January 2011 in “Journal of X-ray science and technology” This study found that perming and bleaching hair result in different distributions of cysteic acid, suggesting distinct damage mechanisms between the two treatments.
7 citations
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May 2010 in “Journal of Cutaneous Pathology” This study identified a novel locus for hereditary hypotrichosis simplex on chromosome 13q12.12~12.3 in a four-generation Chinese family.
4 citations
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March 2000 in “Journal of Investigative Dermatology” The gene for Marie Unna hereditary hypotrichosis is located on chromosome 8p21, near the hairless gene.
1 citations
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July 2016 in “International Journal of Dermatology” This article discusses androgenetic alopecia in Amerindian Mapuche people from southern Chile and reports no new clinical findings.
July 2026 in “Journal of Investigative Dermatology”
January 2025 in “Nature Communications” Using synchrotron X-ray imaging, this study mapped the complex innervation of male rat vibrissa follicles, revealing distinct types of myelinated afferent neurons and patterns of axonal organization that may inform sensory processing in the brainstem.
April 2023 in “Journal of Investigative Dermatology” This study found rapid changes in gene expression in mouse skin cells from the fetal to early postnatal stages, identifying specific markers for different fibroblast types and driver genes in dermal cell differentiation.
January 2019 in “Florida International University Digital Commons (Florida International University)” This research describes using advanced mass spectrometry imaging techniques to analyze gunshot residue and map molecular components in biological samples, such as tumors and mosquito ovarian follicles, at unprecedented spatial resolution and specificity.
January 2024 in “JAAD case reports” This study discusses zinc's vital role in skin cell growth and how its deficiency can lead to acrodermatitis enteropathica, marked by symptoms like alopecia and dermatitis. It notes that similar symptoms appear in people with certain metabolic conditions, referred to as acrodermatitis dysmetabolica.
76 citations
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January 1998 in “Mammalian Genome” 58 citations
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March 2019 in “Frontiers in Pharmacology” This study found that wedelolactone from Eclipta prostrata L. significantly reduced lung inflammation and fibrosis in mice with bleomycin-induced pulmonary fibrosis, suggesting potential therapeutic benefits through AMPK activation.
30 citations
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June 2016 in “Journal of Human Genetics” This study found pathogenic mutations in genes EDA, EDA1R, and EDARADD in 101 out of 124 hypohidrotic ectodermal dysplasia patients, revealing 23 novel mutations and indicating genetic variability.
13 citations
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January 2021 in “Histochemistry and Cell Biology” In this study, human hair follicles showed varying expression of cholesterol transport proteins during the hair cycle, suggesting a potential role of cholesterol in hair growth and cycling.
8 citations
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January 2016 in “Journal of Investigative Dermatology” This review discusses the use of the human-on-mouse xenograft model for studying the human hair follicle cycle and emphasizes its utility for pharmacological testing, without reporting new clinical results.
7 citations
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January 2015 in “Case reports in genetics” This case report illustrates how SNP array testing helped identify a DCAF17 mutation linked to Woodhouse-Sakati syndrome in consanguineous Qatari siblings with shared features including alopecia and hypogonadotropic hypogonadism.
April 2026 in “Experimental & Molecular Medicine” This study used integrated single-cell chromatin and transcriptomic analyses in developing mouse skin to uncover gene networks involved in skin lineage specification and identified Mef2c+ upper fibroblasts as potential precursors to certain muscle-like structures, with cross-species findings in human skin.
December 2025 in “Journal of AI” This study bibliometrically evaluated 5741 articles on PRP from 1980 to 2024, highlighting Türkiye's contribution and identifying prominent research areas such as orthopedics and wound healing.
April 2026 in “Antioxidants” In this study, broccoli sprout extract and sulforaphane were found to reduce cell viability, suppress growth, and induce apoptosis in breast cancer cells, and oral broccoli sprout extract inhibited tumor growth in animal models, suggesting it may be effective in managing breast cancer.
39 citations
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July 1997 in “American Journal of Medical Genetics” This study confirmed linkage of Clouston syndrome in a large Indian family to the 13q11-12.1 region, suggesting it shares a genetic basis with French Canadian cases.
10 citations
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November 2017 in “Letters in drug design & discovery” This paper discusses a structure-based analysis to find new BRD4 inhibitors, identifying finasteride and amentoflavone as promising candidates for BET inhibition.
2 citations
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March 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” This study strongly suggests that a distinct form of hereditary localized alopecia in a Chinese family is linked to a novel locus on chromosome 2p25.1–2p23.2.
October 2021 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” This study found that applying a cosmetic active ingredient improved the Young's modulus of chemically damaged human hair fibers, suggesting enhanced mechanical properties compared to untreated fibers.