Application of XANES Profiles to X-Ray Spectromicroscopy for Biomedical Specimens: Part II. Mapping Oxidation State of Cysteine in Human Hair

    January 2011 in “ Journal of X-ray science and technology ”
    Takafumi Inoue, Kouji Takehara, Norio Shimizu, Yoshinori Kitajima, Kunio Shinohara, Atsushi Ito
    TLDR Perming and bleaching damage hair differently, with bleached hair having more cysteic acid in the cuticle.
    The study utilized XANES profiles to map the oxidation state of cysteine in human hair, focusing on the formation of cysteic acid in permed and bleached hair. It confirmed that cysteic acid forms in homogenized samples of treated hair and used X-ray contact microscopy to chemically map its distribution. The results showed that bleached hair had the highest cysteic acid content in the cuticle region, while permed hair exhibited a more uniform distribution. This indicated that perming and bleaching damage hair through different mechanisms.
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