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research Hair Growth Promotion and Anti-Hair Loss Effects of By-Products Arabica Coffee Pulp Extracts Using Supercritical Fluid Extraction
In this study, the SFE-4 extract from coffee pulp demonstrated potential effects for treating androgenetic alopecia by enhancing cell proliferation and gene expression related to hair growth pathways in vitro, using human hair follicle dermal papilla and prostate cancer cells.
research Fístula arteriovenosa traumática del cuero cabelludo tras implantación capilar tratada con éxito mediante agente embólico PHIL
In this case report, a rare traumatic arteriovenous fistula following hair transplant was successfully treated using percutaneous and endovascular embolization with PHIL, a liquid embolic agent.
research Pruritic axillary papules in a 14‐year‐old girl
This article presents the case of a 14-year-old girl with persistent itchy papules in her armpits and pubic area, awaiting diagnosis details.
research Journal Club: A review of topical and intralesional therapeutics for different types of alopecia
This study found that using a method based on absolute PASI, patients with psoriasis receiving brodalumab had a higher probability of achieving and maintaining a treatment response over 52 weeks compared to those receiving ustekinumab.
research Dermpath & Clinic: Telangiectasia macularis eruptiva perstans
In this study, researchers found that patients with psoriasis had a higher probability of achieving and maintaining a clinical response using brodalumab compared to ustekinumab over 52 weeks, as measured by a multistate modelling approach based on absolute PASI scores.
research Journal Club: Recent therapeutic developments in trichology
In this study, increased treatment duration with vismodegib was associated with a decreased risk of relapse in patients with advanced or multiple basal cell carcinoma.
research Issue Information
research AB0163 ANTI-KU ANTIBODIES: MUCH MORE THAN SCLEROMYOSITIS
This observational study concluded that anti-Ku antibodies do not specifically indicate any systemic autoimmune disease or associated clinical phenotype.
research Uso actual de la vitamina D en dermatología
This article reviews the influence of vitamin D on various dermatological diseases and suggests that vitamin D supplementation might aid in maintaining skin cell homeostasis; it reports no new clinical results.
research Evaluación fotográfica de pacientes con alopecia androgenética tratados con 1 mg de finasterida (Propecia®)
Photography is a simple and effective way to track hair loss treatment progress with finasteride.
research Murgi: un antiguo puerto romano: un antiguo puerto romano
In this study, the vitamin D analogues 1 alpha,25-dihydroxy-vitamin D3 and calcipotriol were found to thin the living cell layer and affect differentiation marker expression in organotypic cultures of human outer root sheath cells.
research Peripheral Skin Temperature and Circadian Biological Clock in Shift Nurses after a Day off
This study found that shift nurses exhibited lower circadian variations compared to daytime nurses, indicating an adjustment of their biological clocks to continuous shift schedules.
research Scientific opinion on the tolerable upper intake level for selenium
This review establishes a tolerable upper intake level of 255 μg/day for selenium in adults, warning that supplements and Brazil nuts may cause excess intake.
research Síndrome do ovário policístico: abordagem dermatológica
This review discusses the pathophysiology, diagnosis, and treatment of polycystic ovary syndrome, emphasizing the critical importance of early diagnosis and treatment to prevent metabolic complications and improve quality of life.
research Association between testicular microlithiasis and primary malignancy of the testis: our experience and review of the literature
Testicular microlithiasis may increase the risk of testicular cancer and patients with it should be closely monitored.
research Hair and cord blood element levels and their relationship with air pollution, dietary intake, gestational diabetes mellitus, and infant neurodevelopment
This study found that exposure to certain elements during pregnancy, measured in maternal hair, was associated with increased risk of gestational diabetes and potential impacts on infant neurodevelopment, with elements like Ta, Re, and Se posing the highest risk for gestational diabetes.
research Comparing the burden of illness in patients with alopecia areata vs atopic dermatitis in the US population from a payer perspective
This study found that patients with alopecia areata had similar total health care costs as those with atopic dermatitis, despite having fewer comorbidities and prescription medications overall.
research The anti‐apoptotic Bcl‐2 protein regulates hair follicle stem cell function
This study found that the anti-apoptotic Bcl-2 protein plays a crucial role in maintaining hair follicle stem cell function and influences tissue regeneration and tumor formation in mice.
research Follicular dysplasia in two cows
This report documents follicular dysplasia with pigmentary changes in two adult cows, contributing to the understanding of this rare condition in cattle.
research Prostaglandin D2 Uses Components of ROS Signaling to Enhance Testosterone Production in Keratinocytes
In this study, PGD2 was shown to increase testosterone production in human keratinocytes through reactive oxygen species, suggesting potential benefits of antioxidants like N-acetyl-cysteine for AGA patients.
research The Diverse Experiences and Challenges of Individuals With Alopecia Areata: Survey Results From Finland
This study found that Finnish individuals with alopecia areata, especially those with significant hair loss, reported reduced well-being and significant comorbidities, highlighting unmet needs for treatment and professional support.
research 697 Prostaglandin D2-enhanced testosterone metabolism in human keratinocytes is mediated by reactive oxygen species
In this study, PGD2 treatment in keratinocytes increased testosterone production via reactive oxygen species, suggesting a potential role for the NRF2 pathway in androgenic alopecia treatment strategies.
research The Scalp as a Donor Site in Pediatric Burns: Systematic Review of the Literature and Proposal of a Management Algorithm
This systematic review concluded that the scalp can be a safe and effective donor site for split-thickness skin grafts in pediatric burn patients, with evidence indicating good scar quality and manageable complications, though a rigorous technique is essential to minimize risks.
research 319 Mechanisms of cell death regulation in hair regeneration
This study found that overexpression of the anti-apoptotic protein Bcl-2 in mice disrupted cell death during the hair cycle, impairing hair regeneration by delaying anagen entry and hair growth.
research DO ANDROGENS MAKE STRAIGHT A STUDENTS?: EXPLORING THE LINK BETWEEN HYPERANDROGENISM AND BLASTOCYST GRADE
In this study, there was no significant difference in blastocyst quality scores between hyperandrogenic and classical PCOS patients undergoing IVF, suggesting other factors might influence the lower embryo utilization in hyperandrogenic cases.
research The dual role of stem cell-specific Bcl-2 function for epidermal regeneration and cancer
This study indicates that the protein Bcl-2 has a dual role, protecting hair follicle stem cells from apoptosis during regeneration and promoting tumor formation under oncogenic stress.
research 013 Prostaglandin D2 enhances testosterone metabolism by ROS-mediated altered redox potential in keratinocytes
This study found that prostaglandin D2 increases testosterone production in human keratinocytes through a mechanism involving ROS and REDOX potential, which could inform treatments for androgenic alopecia.
research 877 Small T antigen from a folliculotropic polyomavirus activates canonical Wnt/β-catenin signaling in vivo
In this study, the authors concluded that the TS-associated polyomavirus may disrupt Wnt/β-catenin signaling, likely contributing to abnormal hair follicle formation in trichodysplasia spinulosa.
research ISID1391 – Cell death functions in hair follicle regeneration
This study found that inhibiting apoptosis during hair follicle regression in mice disrupted hair regeneration, causing delays and alterations in stem cell niche architecture and associated tissue remodeling processes.