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Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

The PCOS-specific questionnaire needs more work to fully measure quality of life in clinical trials.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.

Memantine may slightly improve memory in people with Down syndrome, but more research is needed.

Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.

A 23-year-old woman with Hashimoto’s thyroiditis improved significantly after a 15-month integrative treatment plan.

Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

Intralesional corticosteroids are the best for limited alopecia areata, oral steroids are less effective, and PRP is safe and promising, especially for children and severe cases.

PRP therapy can be effective for early-stage common hair loss, with most patients seeing improvement, but there are inconsistencies in treatment methods.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Syphilis is becoming more common and remains a major health problem due to challenges in prevention and treatment.

Pediatricians should treat some hair loss types in children and refer others to a dermatologist.

Low BMI and cold exposure increase the risk of chilblains.

Lasers are less favored for hair transplant surgery but show promise for hair growth in controlled trials.

Anti-androgens can help manage some PCOS symptoms better than metformin but are not more effective than placebos or birth control pills for other symptoms.

Combining platelet-rich plasma therapy with low dose oral minoxidil improved hair growth in men with hair loss, with slightly higher satisfaction at the higher minoxidil dose.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

The document concludes that hair loss in cats is caused by various factors, including allergies, mites, infections, and hormonal issues, with treatments varying accordingly.

Higher light doses cause more damage to hair follicles, predicting better hair removal results.

Most dermatologists in Western Rajasthan prefer the anti-depressant Doxepin for elderly skin conditions and often refer patients to a psychiatrist.

Some anticonvulsant drugs can cause skin reactions, ranging from mild to severe, and managing these reactions is important for patient care.

Older adults use lifestyle drugs to improve life quality and appearance, but caution is needed due to side effects and potential abuse.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

Hair loss is common in lupus patients and can be permanent or reversible, depending on the type, with various treatments available.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Multi-pass laser skin treatments improved healing, reduced pain, and had no major complications.

Autologous platelet concentrates show promise in esthetic treatments but need more standardized research.

Vacuum massage may improve skin elasticity and induce changes in skin cells, but evidence for treating burn scars is insufficient and more research is needed.