research Inhibition of 5α-Reductase Alters Pregnane Metabolism in the Late Pregnant Mare
Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.
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research Management of Hair Loss Associated with Endocrine Therapy in Patients with Breast Cancer: An Overview
Some breast cancer patients on hormone therapy experience hair loss, and treatments like certain topical inhibitors and supplements may help without harming their cancer prognosis.
research Differential Relationships Between Chronic Hormone Profiles in Pregnancy and Maternal Investment in Rhesus Monkey Mothers With Hair Loss in the Neonatal Period
Monkeys with hair loss during pregnancy showed higher stress hormone levels and invested differently in their offspring.
research Promotion of Mouse Ameloblast Proliferation by Lgr5 Mediated Integrin Signaling
CD61 is important for mouse tooth cell growth and works through Lgr5.
research Safety and Efficacy of Transdermal Testosterone for Treatment of Hypoactive Sexual Desire Disorder
Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.
research Keratin Function and Regulation in Tissue Homeostasis and Pathogenesis
Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
research Drug Safety Evaluation of Exemestane
Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.
research A Clinician's Approach to the Investigation of Otitis Externa
The document concludes that a thorough examination and various tests are crucial for diagnosing and treating ear inflammation in pets.
research In Ovo Injection of CHIR-99021 Promotes Feather Follicle Development via Modulating the Wnt Signaling Pathway and Transcriptome in Goose Embryos
Injecting CHIR-99021 into goose embryos improves feather growth by changing gene activity and energy processes.
research RNA Sequence Analysis of Dermal Papilla Cells’ Regeneration in 3D Culture
3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.
research The Hydroxypropyl-β-Cyclodextrin-Minoxidil Inclusion Complex Improves the Cardiovascular and Proliferative Adverse Effects of Minoxidil in Male Rats: Implications in the Treatment of Alopecia
A new gel form of minoxidil is equally effective for hair growth and safer for the heart and other organs than the traditional solution.
research Indian Gooseberry (Emblica Officinalis Gaertn.) Pharmacological Properties
Indian Gooseberry has potential for cancer prevention and treatment and promotes hair growth.
research Runx Family Genes in Tissue Stem Cell Dynamics
Runx genes are important for stem cell regulation and their roles in aging and disease need more research.
research Early Dengue Virus Infection in Human Skin: A Cycle of Inflammation and Infectivity
Chicken feather gene mutation helps understand human hair disorders.
research Pharmacological Inhibition of DGAT1 Induces Sebaceous Gland Atrophy in Mouse and Dog Skin While Overt Alopecia Is Restricted to the Mouse
Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.
research Highly Upregulated Lhx2 in the Foxn1−/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche
The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.
research Identification of Breast Cancer-Associated Lipids in Scalp Hair
Breast cancer may be detectable through changes in scalp hair lipids.
research Repigmentation of Leukoderma in a Piebald Patient Associated with a Novel c-KIT Gene Mutation, G592E, of the Tyrosine Kinase Domain
A new gene mutation may allow some piebaldism patients to regain skin color in white patches.
research Analysis of the Expression Pattern of the Carrier Protein Transthyretin and Its Receptor Megalin in the Human Scalp Skin and Hair Follicles: Hair Cycle-Associated Changes
The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.
research Topical Fulvestrant Solution Has No Effect on Male and Postmenopausal Female Androgenetic Alopecia: Results from Two Randomized, Proof-of-Concept Studies
Fulvestrant solution doesn't help hair loss in men and postmenopausal women.
research The Role of Androgens in Hormone Replacement Therapy
Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.
research Changes in Growth and Distribution of Hair Associated with Psychotropic Drug Use
Psychotropic drugs can cause hair loss or excessive hair growth.
research Transforming Growth Factor-Alpha Immunoreactivity During Induced Hair Follicle Growth Cycles in Sheep and Ferrets
TGF-alpha is present in sheep and ferret skin and may affect hair growth without directly stimulating cell proliferation.
research Additive In Vivo Growth-Inhibitory Effects of Flutamide and Finasteride on Androgen-Sensitive Shionogi 115 Carcinoma
Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.
research Combinatorial Expression of Cell Cycle Regulators Is More Suitable for Immortalization Than Oncogenic Methods in Dermal Papilla Cells
Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.
research Efficacy of Intralesional and Oral Dutasteride in the Treatment of Androgenetic Alopecia: A Systematic Review
Oral dutasteride works better for hair loss, but has more sexual side effects; intralesional dutasteride is a possible alternative.
research Narrowband UVB Treatment Induces Expression of WNT7B, WNT10B, and TCF7L2 in Psoriasis Skin
Narrowband UVB treatment increases certain gene expressions in psoriasis skin and improves symptoms.
research Norgalanthamine Stimulates Proliferation of Dermal Papilla Cells via Anagen-Activating Signaling Pathways
Norgalanthamine helps hair cells grow by activating certain pathways related to hair growth.
research Testicular Steroidogenesis: Production and Regulation of Testosterone and Dihydrotestosterone
Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.
research Polymorphism in the A2M Gene Associated with High-Quality Milk in Murrah Buffaloes (Bubalus Bubalis)
Certain genetic variations in the A2M gene are linked to better milk quality in Murrah buffaloes.