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Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Mice with a mutated Dsg3 gene showed severe symptoms but not the typical blistering of pemphigus vulgaris.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

Scientists can mimic hair disorders by altering genes in lab-grown human hair follicles, but these follicles lack some features of natural ones.

Skin and hair changes in horses can indicate serious diseases, and recognizing these signs is important for treatment and management.

Feathers are useful for researching growth, regeneration, and the effects of treatments like chemotherapy on hair loss.

Mouse zigzag hair bends form due to a 3-day cycle of changes in hair progenitors and their environment.

Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.

Biotin helps regulate proteins in the blood, which may explain its role in hair growth.

The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.

A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.

Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.

Newly divided skin cells quickly move to join skin structures due to tissue tension and specific signals.

Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.

Keloid skin disorder involves abnormal fibroblast activation and immune response, linked to a group of genes including FGF11.

Blood stem cells are diverse, influenced by many factors, and understanding them is key for progress in regenerative medicine.

Dermal macrophages might help regrow hair.

Mice can regrow hair on wounds due to specific cell interactions and mechanical forces not seen in rats.

Stem cells could improve hair growth and new treatments for baldness are being researched.

Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.

Patients with advanced breast cancer and high hormone receptor levels who had surgery for ovarian/pelvic metastases lived longer, especially if they had high estrogen receptor levels.

Eating nuts, chocolate candy, and red tea might worsen acne, while eating more fresh vegetables could reduce it.

Father's finasteride use may affect son's fertility and testicular function.

Onions may help reduce cancer risk and obesity-related issues.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.

Different human traits like skin color and hair type vary between populations due to genetic adaptations to the environment.

Get head MRI for babies with achondroplasia early, use free immunoglobulin light chains to detect certain neurodevelopmental disorders, and video calls work for speech therapy in patients with facial anomalies.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.