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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

Male hormones worsen kidney transplant damage, but blocking them helps.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Male C57BL/6 mice show age-related fluctuations in certain hormones and their ratios in both blood and hair.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Hair analysis for stress and reproductive hormones in wildlife needs more research for accuracy across species.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

Male rats grow hair faster than females, and certain hormones can slow or slightly increase hair growth, but not significantly beyond natural rates.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

No link found between specific genes and female pattern hair loss.

Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.

Metabolic syndrome linked to urinary symptoms; hair loss not significant.

Male-pattern baldness might be caused by the effect of hormones on scalp blood vessels.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Finasteride and minoxidil together promote hair growth better than either alone.

Measuring reproductive hormones in brown bear hair could help identify their sex and reproductive state, but better collection methods or lab techniques are needed.

Sex hormones affect brain injury differently in males and females.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.

The effects of estrogen on human scalp hair growth are unclear and need more research.