21 citations
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December 1977 in “Journal of pediatric surgery” Individuals with male pseudohermaphroditism often do better raised as females with early surgery.
4 citations
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October 1988 in “Clinics in Dermatology” Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.
124 citations
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September 1992 in “Endocrinology” The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.
76 citations
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September 1992 in “Endocrinology” The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.
2 citations
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January 2007 in “Journal of Labelled Compounds and Radiopharmaceuticals” The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.
94 citations
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April 2002 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.
69 citations
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February 1983 in “Gut” Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.
59 citations
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August 1998 in “International Journal of Dermatology” Genetics and hormones cause hair loss; finasteride treats it safely.
54 citations
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July 2002 in “Clinical and Experimental Dermatology” DHT, a testosterone byproduct, causes male pattern baldness.
40 citations
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September 2008 in “Drug Discovery Today” Current treatments for male pattern baldness include minoxidil and finasteride, with new options being developed.
19 citations
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August 2000 in “International Journal of Dermatology” Minoxidil and finasteride can slow or halt hair loss, but may have side effects.
6 citations
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October 2000 in “International Journal of Dermatology” Preventing hair loss is more effective than regrowth; oral finasteride is a realistic option.
5 citations
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July 2000 in “Southern Medical Journal” Male pattern baldness is often genetic and linked to a hormone, with treatments like finasteride and minoxidil being effective for some men.
203 citations
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February 2005 in “Journal of The American Academy of Dermatology” Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.
122 citations
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July 1990 in “Teratology” Finasteride exposure in pregnancy causes genital abnormalities in male rats.
86 citations
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March 1993 in “Toxicology and Applied Pharmacology” Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.
51 citations
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January 1989 in “Journal of Investigative Dermatology” Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.
46 citations
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October 1999 in “Journal of The American Academy of Dermatology” Finasteride effectively treats male pattern hair loss with a 1 mg daily dose.
38 citations
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April 2011 in “Fertility and Sterility” Finasteride may cause male infertility, stopping it can help.
18 citations
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March 2016 in “The Journal of Clinical Endocrinology and Metabolism” Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.
15 citations
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July 2020 in “Experimental Dermatology” Hormones and genes affect hair growth and male baldness.
9 citations
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March 1985 in “Head & Neck Surgery” Topical minoxidil is the most promising treatment for male pattern hair loss, but more research is needed to confirm its effectiveness and safety.
54 citations
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May 1998 in “Urology” Men with enlarged prostates often have more severe baldness.
32 citations
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September 2015 in “Dermatologic Therapy” Finasteride and minoxidil together work best for male hair loss.
8 citations
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January 1991 in “European Urology” Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.
7 citations
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October 2017 in “The Prostate” Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.
187 citations
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June 1999 in “Journal of The American Academy of Dermatology” Finasteride effectively treats frontal hair loss with few side effects.
55 citations
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March 1990 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.
47 citations
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January 2001 in “Journal of Investigative Dermatology” High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.
35 citations
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September 2012 in “Journal of The American Academy of Dermatology” Finasteride significantly improves hair growth but may cause sexual side effects.