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GlossaryPseudohermaphroditism

condition where genetic sex differs from external genitalia

Pseudohermaphroditism, also known as false hermaphroditism, is a condition where an individual has the genetic and gonadal sex of one gender (either male or female) but has external genitalia that resemble the opposite sex. For example, a person with male pseudohermaphroditism has XY chromosomes and testes but may have external genitalia that appear female. This condition can result from various genetic, hormonal, or developmental factors.

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research Androgen Biosynthesis and Gene Defects

January 2019 in “Elsevier eBooks”

Gene mutations can cause problems in male genital development.

research Sebaceous carcinoma arising at a chronic candidiasis skin lesion of a patient with keratitis-ichthyosis-deafness (KID) syndrome

6 citations , December 2011 in “British Journal of Dermatology”

A man with KID syndrome developed a rare cancer in a long-term skin infection.

Tributyltin (TBT) effects on Ocinebrina aciculata (Gastropoda: Muricidae): imposex development, sterilization, sex change and population decline

research Tributyltin (TBT) effects on Ocinebrina aciculata (Gastropoda: Muricidae): imposex development, sterilization, sex change and population decline

156 citations , October 1996 in “Science of The Total Environment”

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

research Finasteride: The First 5α-Reductase Inhibitor

23 citations , July 1993 in “Pharmacotherapy”

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

research Where it all went right

1 citations , December 2014

Some drugs have gained approval for new uses, while others like tricyclic antidepressants and aspirin show promise but aren't yet approved for these uses.

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community 5 years Dutasteride and Derma Pen only (19-24 y/o)

in Progress Pictures 398 upvotes 1 year ago

The conclusion of this conversation is that the user experienced hair regrowth and increased overall hair thickness after using dutasteride and derma pen treatments for 5 years. They did not experience any side effects.

community My Testosterone results before and after Finasteride

in Update 149 upvotes 2 years ago

Finasteride significantly increased testosterone levels for the user, with no major side effects except watery semen, which was resolved with zinc supplements. The user's hairline stopped receding and slightly improved.

community What an amazing time to be alive

in Finasteride/Dutasteride 187 upvotes 10 months ago

The post discusses a user's experience with hair loss treatments, specifically topical finasteride, minoxidil, and micro-needling, and their plan to switch to oral versions and add Dutasteride. The conversation includes various responses, with some users sharing their own experiences and side effects, and others expressing desire for a more permanent hair loss solution.

community No, Finasteride as a treatment for MPB was not an "accident"

in Research/Science 105 upvotes 3 years ago

Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.