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Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Testosterone's muscle-building effects do not require its conversion to DHT.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Clomipramine may significantly reduce hair-pulling in Trichotillomania, but more research is needed on treatments and early onset cases.

New treatments for male hypogonadism are effective and should be personalized.

Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.

The new biomaterial inspired by ancient Chinese medicine effectively promotes hair growth and heals wounds in burned skin.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.