April 2019 in “Journal of Investigative Dermatology” This study reported that a Maca hydrolysate extract protected human hair follicles from oxidative and inflammatory stress and promoted hair growth in ex vivo models, suggesting a potential use for managing hair loss.
This study found that social hair plucking in captive rhesus macaques was associated with alopecia and exhibited patterns similar to both prosocial and aggressive behaviors.
54 citations
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June 1985 in “American Journal of Dermatopathology” This abstract does not provide specific findings or results.
33 citations
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January 1997 in “Endocrinology” Testosterone was found to inhibit hair follicle epithelial cell proliferation in adult stumptailed macaques only when dermal papilla cells from bald scalps were present, and this effect was reversed by the antiandrogen RU 58841.
21 citations
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June 2016 in “Journal of Medical Primatology” This study observed that management practices affect alopecia and hair cortisol in captive rhesus monkeys, with variations in these effects between different facilities.
19 citations
,
January 1997 in “Endocrinology” This study observed that testosterone inhibits hair follicle epithelial cell proliferation in adult stumptailed macaques only when dermal papilla cells from bald scalps are present, with antiandrogen RU 58841 reversing this effect.
16 citations
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March 2009 in “Skin Pharmacology and Physiology” This study found that the penetration enhancer SEPA™ significantly increased both the speed and amount of hair growth from minoxidil in balding stumptail macaques compared to Rogaine®.
2 citations
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May 2021 in “Scientific Reports” In this study, researchers found that stress likely triggers symmetrical alopecia in Formosan macaques in Mt. Longevity, Taiwan, with higher stress hormone levels associated with the condition.
This study found that social hair plucking in captive rhesus macaques may share traits with both prosocial and aggressive behaviors and is associated with alopecia and hair cortisol levels.
23 citations
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January 2010 in “Journal of Medical Primatology” This study found that alopecia in captive Rhesus macaques may be linked to chronic hypersensitivity dermatitis with CD4+ cell inflammation, possibly influenced by altered housing and reduced pathogen exposure.
21 citations
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October 1988 in “Clinics in Dermatology” This study found that topical minoxidil induced hair regrowth in stumptailed macaques, with more significant effects observed in younger animals, while cessation led to renewed balding and retreatment restored regrowth.
18 citations
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April 1986 in “International Journal of Cosmetic Science” In this study with stumptailed macaques, topical minoxidil successfully induced hair regrowth on bald scalps and prevented baldness on non-bald scalps, with no observed side effects over nearly three years.
17 citations
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November 2013 in “American Journal of Primatology” This study reported species and demographic differences in alopecia rates among macaques, with the highest rates in pigtail macaques and noted age-related improvements in alopecia scores.
11 citations
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May 2019 in “Journal of Medical Primatology” In this study, alopecia was more common among pregnant rhesus macaques compared to non-pregnant controls, and pregnancy was associated with increased hair cortisol levels.
1 citations
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January 1997 in “Journal of Investigative Dermatology” In this study using a macaque model, RU58841 at a 5% concentration significantly increased hair density, thickness, and length in the frontal bald scalp over six months.
33 citations
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January 2014 in “Pediatric Research”
29 citations
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June 2005 in “Journal of Zoo and Wildlife Medicine” This study concluded that coat damage in captive rhesus macaques is unlikely caused by parasitic, bacterial, or mycotic infections but may be linked to environmental or behavioral factors affecting hair growth.
25 citations
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September 1998 in “The Journal of Steroid Biochemistry and Molecular Biology” This study concludes that rhesus macaques are a suitable model for testing the pharmacological properties of finasteride and other 5aR inhibitors, due to their biochemical similarity to humans.
16 citations
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April 2007 in “Journal of Medical Primatology” This study reports that a 14-year-old female rhesus monkey with alopecia universalis was found to have a T-cell-mediated autoimmune disease similar to human alopecia areata universalis.
10 citations
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November 2015 in “American Journal of Primatology” This study found that rhesus macaques with inhibited or anxious temperaments had less alopecia, suggesting temperament may influence hair loss in these animals.
7 citations
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March 2000 in “CRC Press eBooks”
In this study of captive rhesus macaques, social hair plucking was related to kinship, showed characteristics of both prosocial and aggressive behaviors, and was associated with alopecia and hair cortisol concentrations in females.
June 2026 in “Journal of Applied Animal Welfare Science” This study found that social hair plucking in captive rhesus macaques is linked to alopecia and possibly relates to stress in females.
This study observed that in captive rhesus macaques, social hair plucking is linked to alopecia and has kinship patterns similar to grooming, suggesting it may be socially influenced, though the health impacts and stress hormone (cortisol) changes involved remain uncertain.
February 2024 in “Animals” This study observed that alopecia in rhesus macaques follows a seasonal pattern, with the highest hair loss in spring, and varies with reproductive state, as pregnant females experience the most significant alopecia and lowest hair regrowth, which resumes postpartum.
August 2018 in “Archives on veterinary science and technology” This review discusses alopecia in nonhuman primates in research settings and reports no new findings, emphasizing documentation and therapeutic intervention importance during regulatory inspections.
January 2000 in “Hair and its disorders: biology, pathology and management, 2000, ISBN 1853177997, págs. 137-152”
51 citations
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November 2005 in “Journal of Medical Primatology” This study observed that hair loss in captive rhesus macaques varies with season, sex, and housing conditions, and is significantly correlated with HPA axis activity as indicated by faecal cortisol metabolites.
33 citations
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January 2002 This study found that daily topical application of 500 microg/ml latanoprost led to moderate to marked hair regrowth in a macaque model of androgenetic alopecia.
28 citations
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May 2014 in “PubMed” This study found that increased hair cortisol levels, indicating stress, were associated with greater hair loss in captive rhesus macaques, although the causality of this relationship remains unclear.