research First Use of Thymus Transplantation Therapy for FOXN1 Deficiency (Nude/SCID): A Report of 2 Cases
Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.
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research Frontal Fibrosing Alopecia: A Retrospective Clinical Review of 62 Patients with Treatment Outcome and Long-Term Follow-Up
The treatment helped reduce symptoms and stabilize the hairline in most patients with Frontal Fibrosing Alopecia, but hair regrowth was limited.
research Laminin-511 Is an Epithelial Message Promoting Dermal Papilla Development and Function During Early Hair Morphogenesis
Laminin-511 is crucial for early hair growth and maintaining important hair development signals.
research Pharmacology of Antiandrogens
Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
research Genome-Wide Association Meta-Analysis of Individuals of European Ancestry Identifies New Loci Explaining a Substantial Fraction of Hair Color Variation and Heritability
New genetic locations explain much of hair color variation in Europeans.
research Contact Cooling of the Skin
Skin can be cooled quickly and safely during laser treatments to protect it without affecting deeper layers.
research Metformin Improves Polycystic Ovary Syndrome Symptoms Irrespective of Pre-Treatment Insulin Resistance
Metformin helps with PCOS symptoms no matter the patient's initial insulin resistance or weight.
research Glyburide Blocks the Relaxation Response to BRL 34915 (Cromakalim), Minoxidil Sulfate, and Diazoxide in Vascular Smooth Muscle
research The Effect of CD34+ Cell-Containing Autologous Platelet-Rich Plasma Injection on Pattern Hair Loss: A Preliminary Study
Injecting CD34+ cell-containing platelet-rich plasma into the scalp can improve hair count and thickness in people with pattern hair loss.
research Co-Operation Between Follicular Ornithine Decarboxylase and v-Ha-ras Induces Spontaneous Papillomas and Malignant Conversion in Transgenic Skin
High levels of ODC and a mutant Ha-ras gene cause tumors in mice.
research Rickets and Alopecia with Resistance to 1,25-Dihydroxyvitamin D: Two Different Clinical Courses with Two Different Cellular Defects
Patients with this syndrome can have different responses and worsening resistance to treatment over time.
research Female Pattern Hair Loss
FPHL is a common, age-related, genetic hair loss with unclear causes and limited treatment options.
research Uterine Transplantation in Transgender Women
Uterine transplants for transgender women are feasible but need more research.
research Vitamin D Resistant Rickets With Alopecia: A Form of End Organ Resistance to 1,25 Dihydroxy Vitamin D
A girl with rickets and hair loss was found to have a rare condition where her body didn't respond to vitamin D treatment.
research Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes
Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.
research Long-Term Toxicity Studies on Oxidation Hair Dyes
The hair dye formulations tested did not cause long-term toxicity or cancer in mice.
research Unique Amino Acid Signatures That Are Evolutionarily Conserved Distinguish Simple-Type, Epidermal, and Hair Keratins
Different keratin types have unique amino acid patterns that are evolutionarily conserved.
research Rapidly Progressing Mycosis Fungoides Presenting as Follicular Mucinosis
Follicular mucinosis can be an early sign of aggressive mycosis fungoides.
research Androgenic Activity in Autism
Some autistic children may have higher levels of male hormones, which could be linked to aggression.
research Frontal Fibrosing Alopecia: Clinical and Prognostic Classification
Researchers found three patterns of Frontal fibrosing alopecia, with Pattern III having the best prognosis after treatment.
research Regulatory Mutations in TBX3 Disrupt Asymmetric Hair Pigmentation That Underlies Dun Camouflage Color in Horses
Mutations in TBX3 cause horses to have more even hair color instead of Dun camouflage.
research Prevalence of Functional Disorders of Androgen Excess in Unselected Premenopausal Women: A Study in Blood Donors
Many young women who donate blood have hormonal disorders like excess male hormones and PCOS.
research Male Gonadal Function in Coeliac Disease: Sex Hormones
Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.
research Estrogen Functions in Skin and Skin Appendages
Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
research Characteristics Associated with Significantly Worse Quality of Life in Mycosis Fungoides/Sézary Syndrome from the Prospective Cutaneous Lymphoma International Prognostic Index (PROCLIPI) Study
People with mycosis fungoides/Sézary syndrome have a much lower quality of life.
research Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia
Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
research Effects of Finasteride, a Type 2 5-Alpha Reductase Inhibitor, on Fetal Development in the Rhesus Monkey (Macaca Mulatta)
Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.
research Management of Congenital Ichthyoses: European Guidelines of Care, Part Two
European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.
research Wnt Signaling Induces Epithelial Differentiation During Cutaneous Wound Healing
Wnt signaling is crucial for skin wound healing and reducing scars.
research Hidradenitis Suppurativa: A Chronic Inflammatory Skin Condition
Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.