research Pioneer Factors Govern Super-Enhancer Dynamics in Stem Cell Plasticity and Lineage Choice
Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.
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research The Proximal Promoter of the Human Transglutaminase 3 Gene
The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.
research Characterization of a Partial cDNA for Lysyl Hydroxylase from Human Skin Fibroblasts; Lysyl Hydroxylase mRNAs Are Regulated Differently by Minoxidil Derivatives and Hydralazine
Minoxidil decreases LH expression, while hydralazine has mixed effects on prolyl and lysyl hydroxylase activities.
research Minoxidil Exerts Different Inhibitory Effects on Gene Expression of Lysyl Hydroxylase 1, 2, and 3: Implications for Collagen Cross-Linking and Treatment of Fibrosis
Minoxidil affects collagen-related genes, potentially helping treat fibrosis.
research L-Carnitine-L-Tartrate Promotes Human Hair Growth In Vitro
L-Carnitine-L-tartrate may help hair grow and prevent hair loss.
research P75 Neurotrophin Receptor Antagonist Retards Apoptosis-Driven Hair Follicle Involution (Catagen)
Blocking a specific receptor slows down hair loss in mice.
research Structural Features of the Alpha-Type Filaments of the Inner Root Sheath Cells of the Guinea Pig Hair Follicle
α-type filaments in guinea pig hair follicles have unique structural features.
research Modulating Mesenchymal Stem Cell Behavior Using Human Hair Keratin-Coated Surfaces
Coating surfaces with human hair keratin improves the growth and consistency of important stem cells for medical use.
research Getting to the Core of the Dermal Papilla
The document concludes that understanding dermal papilla cells is key to improving hair regeneration treatments.
research Minimum Structural Requirements for Minoxidil Inhibition of Lysyl Hydroxylase in Cultured Fibroblasts
Minoxidil needs specific structure to block lysyl hydroxylase; exploring alternatives may keep benefits without this effect.
research Effects of Minoxidil on Cultured Human Skin Fibroblasts
Minoxidil slows down skin cell growth and may help treat scars and skin conditions.
research XEDAR Activates the Non-Canonical NF-κB Pathway
XEDAR triggers a specific signaling pathway in cells.
research Cross-Linked Features of Mouse Pelage Hair Resistant to Detergent Extraction
Some mutant mice have hair with abnormal cross-linking, mainly in the cuticle, not affecting other hair parts.
research Increased Dipicolinic Acid Production with an Enhanced spoVF Operon in Bacillus Subtilis and Medium Optimization
Genetically modifying a bacteria and changing its growth conditions significantly increased the production of a chemical called dipicolinic acid.
research Demethylation of Methionine and Keratin Damage in Human Hair
Copper and iron cause keratin damage in hair by converting methionine to homocysteine.
research Xenobiotics In Vitro: The Influence of L-Cystine, Pantothenate, and Miliacin on Metabolic and Proliferative Capacity of Keratinocytes
L-cystine, D-pantothenat, and miliacin together significantly boost keratinocyte growth and metabolism.
research High-Resolution Structures of Mutants Affecting Access to the Ligand-Binding Cavity of Human Lipocalin-Type Prostaglandin D Synthase
Mutations in the enzyme don't significantly change how it binds to its specific substances.
research Induction of Dermal Fibroblasts into Dermal Papilla Cell-Like Cells in Hydrogel Microcapsules for Enhanced Hair Follicle Regeneration
Hydrogel microcapsules help create cells that boost hair growth.
research A Keratin Fiber Sheath
Hair fibers may have a unique, non-protein sheath not previously identified.
research Repair of Damaged Hair Protein Fiber by Jointly Using Transglutaminase and Keratin
Using an enzyme and keratin treatment can significantly repair and strengthen damaged hair.
research Hairless-Knockout Piglets Generated Using CRISPR/Cas9 Exhibit Abnormalities in Skin and Thymus
Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.
research Investigating the Relationship Between the Hair Fiber Proteome and Hair Quality
Hair quality is genetically determined and linked to its composition and strength.
research 31-Year-Old Woman With Alopecia
A woman's hair loss was treated successfully with iron supplements for her iron deficiency.
research Is There a Rationale for the Use of Lymecycline for Frontal Fibrosing Alopecia?
Lymecycline may help with Frontal Fibrosing Alopecia but needs more research.
research Gynecologic and Hormonal Comorbidities of Scarring Alopecia: A Retrospective Review
Women with scarring alopecia are less likely to have used hormone replacement therapy or oral contraceptives compared to those with female pattern hair loss.
research Skin Morphogenesis by Coupling Biochemical-Bioelectric Signals: Calcium Oscillations Coordinate Dermal Cell Movement by Epidermis-Derived SHH Signaling During Feather Bud Orientation
Calcium signals and SHH guide the direction of feather growth in chicken skin.
research Dietary Grape Powder Inhibits Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice
Eating grape powder may reduce the severity of skin allergy symptoms.
research Four Closure
Certain astrocytes can protect the brain and improve recovery after a stroke, and a hair loss drug might reduce cancer spread.
research Stroke Recovery: Generation of Highly Pure Astroglia Progenitors from Human Embryonic Stem Cells and Their Neuroprotective Effects
Transplanted human Olig2+ astroglia may help improve learning and memory after a stroke.
research Finding Parallels: Scientific Discoveries in Neuroprotection, Research Self-Efficacy, Metastasis Inhibition, Tumor Suppression, Membrane Channel Regulation, Nanoscale Deformation, and Frequency Shift Detection
Human stem cells can aid stroke recovery, research experiences boost students' career aspirations, minoxidil may reduce cancer spread, a molecule can slow tumor growth, a protein affects water flow in cells, magnesium behaves differently at tiny scales, and a new method detects slow-moving objects.