32 citations,
October 2003 Spironolactone is better than placebo for reducing excessive hair growth in women, but its effectiveness for acne is unclear due to small study sizes.
1 citations,
June 2023 in “Curēus” PCOS affects nearly 25% of female medical and dental students, impacting their academic and social lives.
January 2009 in “Springer eBooks” The document concludes that managing skin conditions during pregnancy is important and requires specialized care.
6 citations,
September 2005 in “Expert Opinion on Pharmacotherapy” Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.
198 citations,
July 2011 in “Cochrane library” Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.
56 citations,
October 1983 in “Archives of Dermatology” Some women with acne have higher levels of free testosterone, which might suggest using hormonal treatments for acne.
1 citations,
January 2013 in “MedChemComm” PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
99 citations,
December 2010 in “Journal of The European Academy of Dermatology and Venereology” The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.
31 citations,
September 2008 in “International Journal of Andrology” 5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.
10 citations,
April 2006 in “Seminars in Reproductive Medicine” Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.
286 citations,
January 2009 in “Human Reproduction Update” Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.
21 citations,
August 1994 in “Clinical endocrinology” 5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.
April 2024 in “JCEM case reports” A woman's rare benign tumor that released both cortisol and testosterone was successfully removed, improving her health.
1 citations,
January 2014 in “Springer eBooks” Adult acne is more common in women, often linked to hormones, and can be harder to treat.
1 citations,
October 2013 in “Journal of Postgraduate Medical Institute” Metformin helps improve menstrual irregularities and some hormone levels in PCOS patients, but not symptoms like excess hair, acne, or hair loss.
15 citations,
January 2015 in “Clinical and Experimental Reproductive Medicine” Taiwanese women with PCOS experience different symptoms based on age, with younger women facing more hormone imbalances and older women dealing with more metabolic issues.
28 citations,
August 2000 in “Current Opinion in Chemical Biology” Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.
June 2024 in “Research Square (Research Square)” Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.
44 citations,
July 2004 in “Archives of Dermatology” Finasteride for hair loss has minimal impact on sexual function.
3 citations,
March 2011 in “Informa Healthcare eBooks” Acne in children varies by age and severity, requires a pediatric treatment approach, and may need diagnostic evaluation for underlying conditions.
January 2016 in “Journal of SAFOG” Girls with PCOS and menstrual disorders have notably higher androgen hormone levels.
18 citations,
October 2017 in “PLOS ONE” The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.
May 2021 in “Journal of Advances in Internal Medicine” A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.
11 citations,
August 2009 in “Expert Opinion on Drug Discovery” We need better ways to test and understand SARMs to make safer and more effective treatments.
2 citations,
October 2008 in “The Journal for Nurse Practitioners” The document concludes that managing PCOS requires a comprehensive approach, including lifestyle changes and medication, to improve symptoms and reduce health risks.
September 2002 in “Comprehensive Therapy” Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.
February 2018 in “InTech eBooks” Diagnosing and treating PCOS is complex due to differing criteria and requires a team approach.
August 2017 in “Journal of epidemiological research” Cancer rates are increasing in developed countries, with estrogen, aging, low vitamin D3, and HPV infection as common causes.
52 citations,
February 2006 in “Current pharmaceutical design” 5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.
4 citations,
August 2017 in “Journal of Cosmetic Dermatology” Finger length ratio may indicate male hair loss.