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The Rotterdam Study investigates diseases in older adults and has produced many research findings.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

PCOS affects a similar percentage of Black and White women in the Southeastern United States.

Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.

Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.

VEGF helps hair grow and determines follicle size by increasing blood vessel growth.

Hair cortisol levels can show increased stress during late pregnancy but only for up to six months.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

A mother's diet at conception can cause lasting genetic changes in her child.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

PCOS affects about 4% of women in the southeastern U.S. equally across Black and White populations.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

Itraconazole is potentially effective for treating invasive aspergillosis, but more research is needed.

Human skin can make serotonin and melatonin, which help protect and maintain it.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.