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Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

Dissolvable microneedles with Ginsenoside Rg3 can help treat hair loss by improving drug delivery and stimulating hair growth.

Azelaic acid micro/nanocrystals, especially with ultrasound and salicylic acid, greatly improve acne treatment.

Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.

Hair greying is seen as a sign of aging; temporary fixes like hair dye are used, but a balanced diet and hair care can help manage it.

Folliculotropic mycosis fungoides has a worse prognosis than other types, with survival rates varying significantly based on subtype and organ involvement.

Hair restoration can be achieved through non-surgical treatments like minoxidil, antiandrogens, phototherapy, and PRP procedures, or through surgical methods like hair transplantation. Continued treatment is needed to maintain results, and full results are visible after 12-18 months.

The document is a detailed medical reference on skin and genetic disorders.

Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.

Lasers are FDA-approved for permanent hair reduction, not removal, and more research is needed to improve treatments.

Cancer treatments targeting specific cells often cause skin, hair, and nail problems, affecting patients' lives and requiring careful management.

Nanotechnology shows promise for better drug delivery and cancer treatment.

Drug repositioning offers hope for new, affordable treatments for a genetic skin disorder called ARCI.

Topical finasteride with EGCG or TA improves drug release and dermal uptake, potentially treating hair loss effectively.

9-cis-retinoic acid showed some effectiveness in treating AIDS-related Kaposi sarcoma but had significant side effects at higher doses.

Ethosomes improve black tea extract absorption in hair dye.

Nanoformulations improve luteolin's effectiveness as a cancer treatment.

Topical retinoids effectively improve photodamaged skin.

Doctors should actively prevent and treat skin side effects in cancer patients to keep them on the best medication and reduce discomfort.

Nanomaterials can improve hair care products and treatments, including hair loss and alopecia, by enhancing stability and safety, and allowing controlled release of compounds, but their safety in cosmetics needs more understanding.

Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.

Ethosomes can safely and effectively deliver various drugs deep into the skin.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

New nanocarriers improve drug delivery for disease treatment.

Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.

New treatments for COVID-19 show promise, but more effective antiviral drugs are needed.

Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.

Scalp cooling effectively reduces hair loss from chemotherapy.

Nanocarrier technology in cosmetics improves ingredient delivery and effectiveness while reducing side effects.