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Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

The document concludes that specific itchy skin diseases during pregnancy have varying fetal risks and treatments, including corticosteroids and other medications.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Some common medications can harm male fertility, but many effects can be reversed.

New treatments for male hypogonadism are effective and should be personalized.

Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.

The new micelle formulation delivers acne treatment more effectively and safely than current gels.

Researchers found 15 new genetic links to skin traits in Japanese women.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

LCN may improve finasteride delivery for hair loss treatment.

The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.

Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Artificial sebum L closely mimics human sebum for drug delivery research.

Lipophilic dyes accumulate more in hair follicles when delivered with surfactant-propylene glycol solutions.

People with atopic dermatitis are more likely to develop other skin conditions due to shared genetics and immune pathways.

Nanotechnology improves hair care products by enhancing ingredient stability, targeting treatment, and reducing side effects, but more research on its toxicity is needed.

The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.