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Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.

The enzyme DHHC13 is essential for healthy hair and skin, and its deficiency leads to hair loss and skin problems.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

The workshop discussed the role of a protein called calreticulin in health and disease, its potential as a treatment target, and its possible use as a disease marker.

Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.

The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

The SbbHLH85 protein helps sweet sorghum grow more root hairs but makes the plant more sensitive to salt.

Using a gene therapy with the Sonic Hedgehog gene helps mice regrow hair faster after losing it from chemotherapy.

Lupus is a complex disease that requires personalized treatment because it varies greatly between individuals.

Signaling pathways are crucial for hair growth in goats.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Certain gene variations in AKT2 are more common in women with PCOS and are linked to higher levels of specific hormones and symptoms.

Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.

Syndecan-1 is essential for maintaining skin fat and preventing cold stress.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Lipases, especially gehB, are crucial for Staphylococcus aureus to enter and colonize hair follicles.

Alkaline Ceramidase 1 prevents early hair loss in mice by keeping hair follicle stem cells balanced.

The supplement with Myo-inositol and D-chiro-inositol improves metabolic symptoms in PCOS, especially when combined with metformin.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

Vitamin D3 is important for hair growth and protecting skin from damage caused by long-term sun exposure.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

ACBP is crucial for healthy skin in mice.