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A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

A genetic mutation caused severe rickets and alopecia in an Indian patient, but high-dose calcium and phosphate treatment improved their condition.

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.

The study found that certain mutations in the vitamin D receptor can cause rickets and potentially affect hair growth.

Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

Tunisian children with hereditary vitamin D-resistant rickets showed improvement with calcium treatment, and new genetic mutations were identified.

A new mutation in the ST14 gene broadens the understanding of ichthyosis-hypotrichosis syndrome.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.

A protein in plants needs to bind two lipids to help with root hair growth, and this process is similar across different plant species.

The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

KATP channels are important for energy balance and are targeted by drugs for diabetes, hypoglycemia, hypertension, and hair loss.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

The document concludes that the androgen receptor's structure and function are complex, affecting how it regulates genes and is involved in diseases like prostate cancer.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

A vitamin D receptor mutation causes rickets and affects immune responses.

Targeting the Smoothened receptor shows promise for treating certain cancers.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.

ACBP is essential for healthy skin and fur by maintaining the skin's barrier function.