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TLR4 is important in aging-related diseases and could be a new treatment target.

Chemotherapy-induced hair loss is a major concern, but various treatments show promise in preventing and reversing it.

Janus kinase inhibitors can regrow hair in alopecia areata but may cause side effects and hair loss may return if treatment stops.

Early genetic testing and JAK inhibitors can help treat systemic inflammation in SAVI patients.

Metabolic signals and cell shape influence how cells develop and change.

Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Blocking YAP/TAZ could be a new way to treat skin cancer.

A special receptor in sensory nerve endings helps control how they respond to stretching.

Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.

Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

JAK inhibitors show promise for treating various skin diseases.

Hedgehog signaling controls hair follicle development and can affect skin cancer growth.

Apoptosis, not oxidative stress, is linked to aging in mice with mtDNA mutations.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

TGFβ signaling prevents sebaceous gland cells from producing fats.

Frizzled 3 and Frizzled 6 together control the orientation of mouse hair follicles.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

The workshop discussed the role of a protein called calreticulin in health and disease, its potential as a treatment target, and its possible use as a disease marker.

Testosterone Replacement Therapy can improve sexual health in postmenopausal women with low sexual desire, but more research is needed on its long-term effects.

Collagen is crucial for health and treating certain diseases, and supplements can improve skin, nails, and hair conditions.

Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.

Dermal factors are crucial in regulating melanin production in skin.

New tools show that in fish, NPY increases feeding and somatostatin decreases it.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Overexpressing follistatin in mice delays wound healing and reduces scar size.

Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.