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Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Dermatological conditions are complex, and treatments have mixed results.

The 308-nm excimer laser is a promising treatment for vitiligo with varying success and mild side effects.

Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.

Celiac disease can cause skin problems that may get better with a gluten-free diet.

Hair follicle hyperplasia is common in both benign and malignant skin lymphoproliferative disorders, with a proposed new term "pseudolymphomatous adnexitis."

Autoimmune liver diseases are likely linked to certain skin conditions like vitiligo and psoriasis.

The Arabic Skindex-16 is a reliable and valid way to measure the impact of skin conditions on quality of life in Saudi patients.

Scalp biopsies from dermatomyositis patients show chronic hair loss without scarring, with mucin and blood vessel changes being very common.

Most hospitalized children with skin issues were boys, with allergic skin diseases like atopic dermatitis being most common, and treatments were usually topical.

CD8+ T cells play a key role in graft-versus-host disease in certain mice models.

Some immunosuppressed patients can get unusual skin infections from Malassezia, which can be treated with antifungal medication.

Most dogs with paw inflammation had chronic issues, often due to allergies, and certain breeds were more affected.

A woman with lupus and systemic sclerosis developed severe acne that didn't improve with treatment and died from pneumonia and septic shock.

The document concludes that secondary syphilis cases are increasing and often misdiagnosed, pityriasis rubra pilaris can be distinguished from psoriasis by skin cell features, and different skin layers produce specific components during skin repair.

YN oil combined with Rhinacanthus nasutus leaf is an effective and safe treatment for dog skin disease.

Hair color is influenced by genetics and can indicate certain health conditions.

UVB is good for a skin condition in Asian kids, a lotion works for head lice, a drug helps with a skin blistering disorder, a foam reduces itchiness in skin inflammation, birthmarks can be more widespread, and criteria for a neurocutaneous disorder were agreed upon.

Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.

A brown shadow seen in dermoscopy is a marker for lichen nitidus.

Grateloupia elliptica extract may help prevent hair loss and promote hair growth.

Methotrexate is effective and well-tolerated in children for certain skin conditions but requires careful monitoring.

The conclusion is that a team of skin doctors and psychiatrists is needed to better treat patients with mind-skin disorders.