TLDR Hair color is influenced by genetics and can indicate certain health conditions.
Hair pigmentation significantly affects visual appearance and social interactions, with melanin producing various hair colors. Follicular melanogenesis relies on genetic, biochemical, and physical factors, as well as epithelial-melanocytic interactions. Genetic changes, pigment transfer defects, and impaired signaling pathways can lead to clinical conditions. The document updates recent scientific advances in follicular melanogenesis and its pathological changes related to specific diseases.
450 citations
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January 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color is determined by melanin produced and transferred in hair follicles.
47 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Premature graying of hair may suggest health issues and currently lacks effective treatments.
12 citations
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September 2018 in “International Journal of Cosmetic Science” Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.
2 citations
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January 2017 in “Journal of Pigmentary Disorders” Genetics, stress, and health issues can cause early hair greying, which affects self-esteem, and there's no cure, only hair dye.
349 citations
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January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
