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Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Hidradenitis Suppurativa is likely an autoinflammatory disease, and better understanding its causes could improve treatments.

Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

The document explains how male reproductive hormones work and affect the body.

Men with early balding should be checked for metabolic syndrome, as there's a link between the two.

Zebrafish helped find new ways to prevent drug-induced hair cell death and potential treatments for hearing loss.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

PTHRP agonists can stimulate hair growth, especially in damaged follicles, while antagonists may initially increase growth but ultimately inhibit it.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

The testes produce sperm and hormones essential for male development.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.

Herbal treatments can help manage PCOS symptoms.

Sulforaphane from broccoli may help treat certain cancers, hormone issues, and hair loss.

The document concludes that drug repurposing, which is reusing known medicines for new illnesses, can provide faster, cheaper treatment options for various serious diseases, including cancer, COVID-19, and rare diseases.

Cyproterone acetate with ethinyl estradiol is effective for treating skin symptoms related to high androgen levels, like in PCOS.

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.