May 2023 in “Journal of Clinical Medicine” This review article reports recent advancements in understanding, diagnosing, and treating various hair loss conditions, like androgenetic alopecia and alopecia areata, including their genetic factors and new therapeutic options, while also examining the impact of COVID-19 on hair loss.
January 2020 in “Acta Scientiae Veterinariae” In this case report, a combination of ozone therapy, low-level laser, and herbal medicine gel effectively improved healing in a dog with chronic bite wounds.
December 2024 in “Medical alphabet” This study concludes that a combined therapy of erbium laser, transcutaneous laser blood irradiation, and minoxidil had the greatest impact on improving microcirculation efficiency in patients with diffuse telogen effluvium.
1 citations
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April 2018 in “Lasers in Surgery and Medicine” This review summarizes late-breaking abstracts from the American Society for Laser Medicine and Surgery, 2018, and reports no new clinical findings.
19 citations
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February 2018 in “Lasers in Medical Science” This study found that 655-nm red light with LED enhanced hair shaft elongation and reduced catagen transition in human hair follicles in vitro by activating the Wnt/ß-catenin signaling pathway.
23 citations
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September 2011 in “Journal of Dermatological Science” This study explored the effects of a new narrow-band red LED light on hair growth in mice, showing potential benefits compared to existing laser therapies.
62 citations
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July 2018 in “Lasers in Medical Science” In this review, the researchers highlight LED therapy as an emerging and safe treatment for skin inflammatory conditions, aging, and hair growth disorders, noting its integration into dermatological practice but emphasizing the need for more controlled studies to confirm its efficacy.
December 2025 in “Journal of Education Health and Sport” This study reports that LED phototherapy is gaining popularity as a safe and effective non-invasive method for treating various skin conditions, enhancing skin rejuvenation, wound healing, and inflammation modulation, and is increasingly integrated into clinical protocols for conditions like acne vulgaris and signs of aging.
4 citations
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February 2014 in “Proceedings of SPIE” This review discusses the diverse applications of low-level laser therapy in aesthetic dermatology, especially for managing alopecia, but notes that comprehensive literature on its effectiveness is lacking.
January 2026 in “Journal of Hard Tissue Biology” This study found that red LED photobiomodulation significantly enhanced both the metabolic activity and proliferation of human placenta-derived pericytes, alongside increased expression of angiogenic markers, suggesting a potential non-invasive approach to aid tissue repair and vascular regeneration.
November 2025 in “Revista Multidisciplinar do Nordeste Mineiro” This study's review of existing literature suggests potential benefits of red LED photobiomodulation for treating telogen effluvium, but highlights a lack of standardized parameters and calls for further controlled trials.
September 2017 in “Springer eBooks” Low-level laser therapy seems to promote hair growth but requires more research to confirm its effectiveness.
165 citations
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August 2013 in “Lasers in Surgery and Medicine” This review discusses the potential mechanisms and evidence supporting low-level laser therapy for stimulating hair growth in men and women, while noting its safety and effectiveness but needing further study on specific parameters.
2 citations
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January 2018 in “Recent clinical techniques, results, and research in wounds” This review discusses the effects of low-level laser therapy in various biological processes for wound healing and tissue repair and reports no new results.
17 citations
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December 2015 in “International Journal of Cosmetic Science” This review discusses the effectiveness of non-thermal, non-ablative devices like light-emitting diodes in treating various skin and hair conditions but reports no new clinical findings.
14 citations
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November 2022 in “Archives of Dermatological Research” This study found that a green-light LED microneedle patch enhanced hair growth in mice with the best results among tested wavelengths, showing increased hair follicles and no serious side effects, suggesting its potential for treating androgenetic alopecia.
1 citations
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March 2024 in “Brain Imaging and Stimulation” This study reported that a 3D-printed LED photobiomodulation device is technically and financially feasible, but requires further experimental and clinical testing before being used in human healthcare.
December 2025 in “Aesthetic Plastic Surgery” This study reported that the new near-infrared LED device showed significant improvements in skin rejuvenation and a slight increase in hair growth, with further research recommended for broader validation.
October 2024 in “Photodermatology Photoimmunology & Photomedicine” In this study, participants with androgenetic alopecia who used an LED helmet emitting red and green light experienced significant improvements in hair growth measures, with red light showing superior results in increasing hair diameter and reducing vellus hair density over 6 months.
June 2017 in “Journal of The American Academy of Dermatology” LED light helps hair follicle cells grow and prevents them from dying by activating certain cell pathways.
May 2017 in “Journal of The American Academy of Dermatology” LED light helps human hair root cells grow and move by activating certain cell pathways.
May 2017 in “Journal of The American Academy of Dermatology” LED light helps human hair root cells grow and prevents them from dying by activating specific growth pathways.
8 citations
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November 2020 in “Optics and Laser Technology” This review discusses the applications and advantages of LED-based photobiomodulation therapy for dermatological and cosmetic purposes but highlights existing challenges and health concerns while exploring future perspectives.
November 2025 in “SKIN The Journal of Cutaneous Medicine” This review highlights the potential benefits of low-level light therapy for treating various alopecias, with reported improvements in hair density and count, especially when combined with minoxidil or finasteride, but it offers no new clinical results.
April 2018 in “International journal of nanotechnology and nanomedicine” In this double-blind, placebo-controlled study, researchers found that low-level laser therapy significantly improved the healing rate and reduced the area of pressure ulcers in patients compared to placebo, suggesting its effectiveness in managing ulcers resistant to conventional treatments.
160 citations
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December 2016 in “Journal of biophotonics” This review discusses the evolution and potential of photobiomodulation therapy, highlighting its transition from skepticism to recognition in medical research; it reports no new experimental findings.
33 citations
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March 2017 in “Dermatologic Surgery” In this clinical study, low-level laser therapy using the HANDI-DOME LASER device increased hair counts by 51% compared to controls, indicating its potential as a safe and effective treatment for androgenetic alopecia in women aged 18 to 60.
33 citations
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January 2017 in “Annals of Dermatology” This study suggests that LED light may promote the proliferation of human dermal papilla cells through the activation of specific signaling pathways.
24 citations
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March 2015 in “Dermatologic Surgery” This review discusses the modest efficacy of home-use laser and light devices for conditions like hair removal and acne, noting limited evidence and a lack of robust trials.
21 citations
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August 2013 in “Journal of Dermatological Treatment” This review discusses the mixed evidence and high risk of bias in studies on low-level light therapy for treating androgenetic alopecia and calls for rigorous randomized controlled trials to assess its efficacy.