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Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Current treatments for alopecia show no significant long-term benefits.

Stem cell niches support, regulate, and coordinate stem cell functions.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.