17 citations
,
January 1993 in “Journal of Gastroenterology and Hepatology” This study found that recombinant IFN α-2b injections in patients with acute post-transfusion hepatitis C can suppress viral RNA and lead to normalization of serum ALT, though long-term prevention of chronicity remains unclear.
16 citations
,
May 2020 in “Frontiers in pharmacology” This study found that minoxidil stimulates the Kir6.2/SUR2 potassium channel, leading to tumor growth arrest in an ovarian cancer xenograft model by disrupting mitochondrial function and inducing cell death.
16 citations
,
October 2004 in “Acta dermato-venereologica” This article provides information about the University of Bologna's departments involved and includes contact details for the lead author, but it presents no research findings.
16 citations
,
February 2001 in “PubMed” This study found that allergic contact dermatitis of the scalp may cause telogen effluvium, leading to mild to moderate hair loss in some patients.
15 citations
,
June 2015 in “Journal of Craniofacial Surgery” This study suggests that surgical intervention for scalp infantile hemangiomas, often necessary due to complications like alopecia and ulceration, generally leads to good aesthetic outcomes and satisfactory hair growth.
14 citations
,
May 1988 in “The Journal of Dermatologic Surgery and Oncology” This report describes three cases of postoperative necrosis following bilateral lateral reduction surgery, leading the author to discontinue the procedure and advise caution to others.
13 citations
,
September 2017 in “Skin appendage disorders” Some women with Frontal Fibrosing Alopecia also have Lichen Planopilaris, which can lead to more symptoms and affect hair outside the scalp.
13 citations
,
September 2017 in “Oncotarget” This study suggests that increased Wnt signaling may cause melanocyte stem cell exhaustion, leading to hair graying in aged mice by promoting excessive differentiation of melanocytes.
13 citations
,
September 2013 in “Steroids” This study found that a commonly-used DHT enzyme immunoassay shows significant cross-reactivity with testosterone, leading to inaccurate DHT measurements compared to a gold-standard LC–MS/MS method.
12 citations
,
January 2017 in “PubMed” This case study reports a possible link between gastroparesis and reduced absorption of thyroxine, leading to persistent hypothyroidism despite increased medication doses.
11 citations
,
March 2016 in “PubMed” This article highlights that tinea capitis in adults is often misdiagnosed, leading to treatment delays, and suggests fungal testing for those unresponsive to seborrheic dermatitis or psoriasis treatments.
11 citations
,
July 2015 in “Frontiers in Cellular Neuroscience” This study found that corticosterone promotes neurosteroid synthesis in hippocampal neurons, which can lead to ethanol-mediated synaptic dysfunction even at moderate ethanol levels, potentially contributing to stress-related cognitive impairment from alcohol.
10 citations
,
September 2020 in “Metabolites” This study found that metabolite levels in hair samples differ significantly by hair color and segment, leading to recommendations for best practices in hair metabolomic studies.
10 citations
,
November 2018 in “The Italian Journal of Pediatrics/Italian journal of pediatrics” This case report identifies a mutation in the TRPS1 gene, leading to the diagnosis of trichorhinophalangeal syndrome type I in a young girl and her family, highlighting the importance of detailed clinical and family history for proper diagnosis.
9 citations
,
August 2024 in “Tissue Engineering and Regenerative Medicine” In this study, researchers suggest that strategic early intervention during fetal wound healing could lead to significantly improved long-term skin regeneration outcomes.
9 citations
,
November 2007 in “Blood” This study found that a mutation in the Tmprss6 gene disrupts hepcidin regulation, leading to iron deficiency and alopecia in mice, highlighting TMPRSS6's vital role in iron absorption.
8 citations
,
May 2024 in “PLoS Biology” This study on feather pattern formation in chicken skin found that inhibiting gap junctional intercellular communication can lead to the emergence of new feather buds in specific spatial patterns, suggesting that GJIC may facilitate Turing-type periodic patterning by propagating inhibitory signals over long distances.
8 citations
,
February 2021 in “Journal of the American Heart Association” This study observed that medical castration for prostate cancer prolongs the QT/QTc intervals, potentially leading to serious arrhythmias like torsade de pointes and ventricular fibrillation, even in patients without prior QT prolongation risk.
8 citations
,
January 2017 in “Stem Cells International” This study found that overexpression of sFRP4 in skin cells reduces Wnt signaling activation, leading to decreased melanocyte differentiation in regenerating hair follicles.
8 citations
,
October 2016 in “Experimental dermatology” This paper proposes that the induction of HF-specific neo-antigens by peripheral CD8+ T cells may maintain self-tolerance but could also lead to immunopathology in conditions like alopecia areata.
7 citations
,
November 2021 in “Anais Brasileiros de Dermatologia” This retrospective study found a variety of dermatological adverse events associated with antineoplastic treatments, often leading to changes or suspension of cancer therapies in affected patients.
7 citations
,
August 2021 in “Journal of the European Academy of Dermatology and Venereology” This study suggests that early initiation of treatment in fibrosing alopecia in a pattern distribution may lead to a more favorable outcome, as evident in some patients experiencing arrested disease progression and hair regrowth.
7 citations
,
October 2010 in “Medical Hypotheses” Alopecia areata may involve stress-related changes affecting hormone receptors, leading to reduced cortisol production.
6 citations
,
November 2024 in “Medicine International” In this systematic review, researchers reported that post-COVID-19 syndrome can lead to various dermatological symptoms, including skin rash, alopecia, pruritus, and dermatitis, with a notable prevalence of autoimmune-related skin changes, especially among females and those with severe COVID-19 history.
6 citations
,
January 2016 in “Menopause” Estrogen deficiency, like after menopause or certain surgeries, leads to faster skin aging and health issues.
6 citations
,
October 2011 in “PubMed” This study evaluated stress responses in police officers working shifts, focusing on how stressful factors lead to various signs and symptoms, but reports no new results.
6 citations
,
October 1989 in “PubMed” This study describes optimized methods for culturing hair cells from 4-day-old C3H mice, leading to successful maintenance of hair-specific cytoskeletal protein expression under the experimental conditions.
6 citations
,
May 1941 in “Science” Ducks can get the Rous sarcoma virus if infected shortly after birth, leading to tumors and disease spread.
5 citations
,
May 2024 in “Australasian Journal of Dermatology” This study found that alopecia areata significantly impacts both emotional and psychosocial well-being, leading to impaired productivity in adults and adolescents, especially those experiencing more extensive hair loss.
5 citations
,
August 2021 in “The Journal of the American Animal Hospital Association/Journal of the American Animal Hospital Association” This study observed that accidental topical minoxidil exposure can cause toxicosis in dogs and cats, leading to moderate or major illness, and even death in some cats.