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Intralesional chemotherapy with 5-fluorouracil and methotrexate may worsen keratoacanthoma-type skin cancer in transplant patients.

Skin stem cells can help improve skin repair and regeneration.

Tiny particles from skin cells can help activate hair growth.

Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.

Higher levels of nidogen1 and type IV collagen are found in basal cell carcinoma compared to normal skin.

CREB, a protein that can promote cancer traits, is controlled by β-catenin in skin cancer cells.

The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.

FOL-005, a hair growth promoter, acts locally on mouse skin where injected and could be a promising hair loss treatment.

Hair disease research is a growing and evolving field in dermatology, with recent significant advances.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

Removing part of the vitamin D receptor stops vitamin D from working properly.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Different types of skin cells play specific roles in development, healing, and cancer.

Lactate production is important for activating hair growth stem cells.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

TCDD speeds up skin barrier formation by increasing certain gene expressions.