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The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

HFMs can help study hair growth and test potential hair growth drugs.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

Wound healing insights can improve regenerative medicine.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Cell-based therapies show promise for treating Limbal Stem Cell Deficiency but need more research.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

Artificial skin is improving wound healing and shows potential for treating different types of wounds.

Cultured dermal papilla cells can regenerate hair follicles and sustain hair growth.

Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

Insulin helps heal corneal wounds and nerves in diabetic mice by activating the Wnt signaling pathway.