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Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Enzyme injections can effectively treat epidermoid cysts without surgery.

Minoxidil treatment increases aorta elasticity and reduces stiffness in aged mice, potentially helping with age-related heart issues.

Hair follicles and deer antlers regenerate similarly through stem cells and are influenced by hormones and growth factors.

Stephen Rothman made important discoveries in dermatology, including the use of PABA in sunscreens, but never profited from his work.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

Using powdered umbilical remnant allograft can effectively treat chronic scalp wounds resistant to traditional treatments.

Some patients taking antipsychotic medications experience skin reactions, ranging from mild to severe.

Keratin peptides can change hair shape gently without harsh chemicals.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

Electrical epilation damages hair follicles and surrounding skin, likely preventing hair regrowth.

Both cell and non-cell parts are important for rat whisker follicle regrowth.

Notch signaling is essential for healthy skin and hair follicle maintenance.

Older women face various skin issues like dryness and thinning, and treatments are available but can have side effects; proper skin care and legal health decisions are important.

The document concludes that various childhood hair and nail disorders exist, some may improve on their own, and advances in genetics and immunology could enhance treatment and counseling.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Shampoos clean hair mainly with surfactants and have added ingredients for extra benefits.

Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.

A new gene mutation linked to a skin condition was found in a Spanish family.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

The document concludes that hair analysis is not good for assessing nutrition but can detect long-term heavy metal exposure.

Surfactants in shampoos and conditioners remove some but not all lipids from hair, and more research is needed to understand their full impact.

Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.

Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.

Ethosomes are a promising way to deliver drugs through the skin.

The same genetic mutation in Sjögren-Larsson syndrome can lead to different levels of severity, suggesting other factors influence the symptoms.

Nanostructured delivery systems could potentially improve hair loss treatment by targeting drugs to hair follicles, reducing side effects and dosage, but the best size, charge, and materials for these systems need further investigation.

Transglutaminase activity is important for skin and is found in both mammals and birds.