research Terminalia Chebula Fruit Extract From PSR Technology Demonstrates Strong Anti-Aging and Antioxidant Properties
Terminalia chebula fruit extract has strong anti-aging and antioxidant effects.
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research HPV8 E6 Induced STAT3 Activation Leads to Hair Follicle Junctional Zone Keratinocyte Stem Cell Proliferation and Expansion in Actinic Keratoses
HPV8 causes hair follicle stem cells to grow, leading to skin lesions.
research Uncoupling Desmosomal Cadherin Adhesion Activates Quiescent Hair Follicle Stem Cells and Orchestrates Self-Organized Regeneration Through Outside-In Signaling
Disrupting a specific protein's function in hair follicle stem cells triggers their activation and a self-healing process.
research Basal Keratinocytes Exhibit Age-Related Epigenetic and Transcriptomic Alterations Resulting in an Altered Metabolic Profile
Aging changes skin cells, leading to different DNA methylation and gene activity, affecting cell metabolism and aging signs.
research Response to Ritlecitinib Treatment Based on Salt Improvement Scores in Patients With Alopecia Areata: Post Hoc Analysis of the Allegro Phase 2b/3 Study
Ritlecitinib significantly improves scalp hair regrowth in alopecia areata patients over time.
research Autophagy Controls the Protein Composition of Hair Shafts
Autophagy is important for determining the protein makeup of hair.
research Spectrum Changes of Pediatric Dermatological Disorders Before and During the COVID-19 Pandemic in China: A Single National Center for Children's Health Experience
During the COVID-19 pandemic in China, skin conditions like eczema and warts increased among children, while respiratory-transmitted skin infections decreased, partly due to mask-wearing.
research Epidermal Growth Factor Receptor Protects From Immune Privilege Collapse and Scarring Hair Follicle Destruction
Blocking EGFR can lead to hair loss due to inflammation and stem cell damage.
research Comorbid Conditions Associated With Alopecia Areata: A Systematic Review and Update
People with Alopecia Areata are more likely to have certain health issues like ulcerative colitis and type 1 diabetes, but less likely to have others like hypertension and type 2 diabetes.
research Clinical Technique and Outcomes of Platelet-Rich Plasma Application for Treatment of Androgenic and Scarring Alopecia, Acne Scarring, Melasma, and Facial Rejuvenation: A Prospective Multicenter Study
Platelet-rich plasma treatment is generally safe and effective for hair loss, acne scars, skin discoloration, and facial rejuvenation, but deeper injections are better and multiple treatments can increase risk of side effects.
research A Quantitative Study of Desquamation in the Stratum Corneum
New method measures skin cell turnover quickly and effectively, showing turnover slows with age and responds more to treatments in older skin.
research Fate Tracing of DNA-Damaged Hair Follicle Stem Cells and Their Seno-Differentiation Clearance Out of the Niche
Damaged hair follicle stem cells may leave the skin to help maintain youthfulness.
research Single-Cell Transcriptomics Reveals Distinct Molecular Programs in Folliculotropic Mycosis Fungoides
Folliculotropic mycosis fungoides has unique molecular features and cell interactions that could guide targeted therapy.
research A Novel Investigator Global Assessment Score for the Evaluation of Keratosis Pilaris
The document's conclusion cannot be provided because the content is not accessible.
research Use of Calcitonin Gene-Related Peptide Monoclonal Antibodies in Patients With Rosacea: An Exploratory Comparative Case Series
CGRP MAbs treatment for migraines may also improve rosacea symptoms, but more research is needed to confirm its effectiveness and safety.
research Prospective Study of the Metabolic Effects of Tumescent Liposuction
Tumescent liposuction reduces waist and hip size but doesn't significantly change metabolic markers, though it may slightly improve blood pressure and certain protein levels.
research Functional Roles of Krox20 (Egr2) in Epithelial Stem Cells
Krox20 (Egr2) is important for the function of epithelial stem cells.
research Impact of Temperature on Sprouted Seeds in Botanical Extracts Obtained With Different Extraction Processes
Cold temperatures reduce sprouted seed extract yield, but PSR™ technology produces extracts with more beneficial compounds than conventional methods.
research Single-Cell Transcriptomic Profile of EGFR-Deficient Epidermal Compartments During Folliculitis
EGFR deficiency causes significant changes in skin cells and hair follicles.
research H3K9me3 Methyltransferase SETDB1 Controls Retrotransposon Silencing, DNA Methylation, Constitutive Heterochromatin Maintenance and 3D-Chromatin Structure in Epidermal Keratinocytes
SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.
research Neutrophil Elastase Is Critical In Linear IgA Bullous Dermatosis In Mice
CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss.
research Empathic Disequilibrium Is Related to Lower Levels of Oxytocin in Hair
People with an imbalance between their cognitive and emotional empathy have lower levels of the hormone oxytocin in their hair.
research Design of a New Molecule Proven to Be Safe and Effective for Topical Depigmenting and Antiaging Method
A new molecule was found to be a safe and effective skin lightener and anti-aging product.
research Combining Laser Capture Microdissection and RNAseq Analysis to Generate a Human Anagen Hair Follicle Transcriptome Atlas
Researchers made a detailed map of gene activity for different parts of human hair follicles to help create targeted hair disorder treatments.
research The Striatin-Interacting Phosphatase And Kinases Complex Is Important for Skin Epidermal Differentiation and Barrier Formation
The STRIPAK complex is crucial for skin cell organization and creating a functional skin barrier.
research Tyrosine Kinase 2 Inhibition Ameliorates the Phenotype of Lesional Alopecia Areata Scalp Skin Ex Vivo, and Reverses the Induction of Human Alopecia Areata in a Humanized Mouse Model
TYK2 inhibition may help treat alopecia areata by promoting hair growth and reducing immune response.
research Varicella-Zoster Virus in Actively Spreading Segmental Vitiligo Skin
The study suggests a link between varicella-zoster virus and segmental vitiligo, with evidence of the virus disrupting skin pigment cells.
research Mechanisms of Cutaneous Adverse Events During Targeted Cancer Therapy
Targeted cancer therapies can cause skin side effects, but activating SOS in the skin may help reduce them.
research Sephardic Ancestry in Recessive Dystrophic Epidermolysis Bullosa Individuals Carrying the Prevalent c.6527insC Mutation
Most Recessive Dystrophic Epidermolysis Bullosa patients with a specific mutation likely have Sephardic ancestry from about 500 years ago.
research Dynein Is Involved in the Movement, Distribution, Acidity, and Transfer of Melanosomes
Dynlt3 is important for melanosome transport and skin coloration.