Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that finasteride decreased plasma dihydrotestosterone levels and altered steroid metabolism, similar to the profile of male pseudohermaphrodites with inherited 5a-reductase deficiency.

Among families with pediatric brain disease, this study identified over 200 novel genetic causes, revealing potential treatment points using drug repurposing or nutritional supplementation.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

This study found that finasteride effectively reduced hirsutism in women during 12 months of treatment, with some effects persisting in the majority after stopping the medication.

This study suggests that daughters of women with PCOS may have altered androgen metabolism in early childhood, with increased 5α-reductase activity potentially contributing to PCOS development.

This study found that finasteride treatment significantly reduced hirsutism scores in women with idiopathic hirsutism over 6 months and was well tolerated.

In this study, differences in protein expression related to twin lambing were identified in Tibetan sheep, providing insights into the reproductive performance and fertility improvement strategy for sheep in the Qinghai-Tibet Plateau.

This research found that androgen bioactivity plays a role in normal female sexual differentiation, suggesting females develop within a significant androgenic environment, with implications for understanding conditions like congenital adrenal hyperplasia.

This review discusses the dual role of extracellular vesicles in Alzheimer's disease, highlighting their potential in both exacerbating and alleviating the condition, and emphasizes the need for advanced technologies to enhance diagnosis and treatment.

This research highlights the crucial roles of B vitamins in metabolism, neurological processes, and DNA functions, and describes emerging therapies that enhance vitamin absorption and therapeutic potential.

This study observed that, among alopecia areata patients in Fujian, China, lower IgG4 levels and higher IFN-γ levels were statistically significant, suggesting their potential role as biomarkers for the condition and highlighting avenues for future therapeutic developments.

This review discusses the potential health benefits of L-Cysteine, noting increased research interest but highlighting a lack of clinical trial data for consensus on its effectiveness.

This study found that oral administration of l-cystine with vitamin B6 effectively prevents environmental cigarette smoke-induced alopecia in mice by reducing hair bulb cell apoptosis.

This study observed that fibrin rich in leukocytes and platelets (L-PRF) might effectively heal diabetic foot ulcers with osteomyelitis, showing positive preliminary results in all three patients treated.

In this study, l-Ascorbic acid 2-phosphate was found to stimulate hair follicle growth in vitro by promoting IGF-1 expression via the PI3K pathway.

This study identified a new enzyme, skin l‐tryptophan‐2,3‐dioxygenase, that may play a role in rat hair growth regulation, showing increased activity during peak hair growth periods.

In this study, L-threonate was found to inhibit DHT-induced DKK-1 expression in cultured dermal papilla cells, suggesting it could help prevent androgen-driven balding.

In this study, researchers found that L-cysteine interacted electrostatically with anionic ions on the surface of keratin fibers in human hair, reducing the rate of disulfide bond disconnection at pH 9.0.

This study found that both finasteride and dutasteride significantly reduced L-DOPA-induced dyskinesia in a rat model of Parkinson's disease, with dutasteride showing greater effectiveness at lower doses.

This study found that l-carnitine stimulated hair growth in vitro by promoting proliferation and reducing apoptosis in human scalp hair follicles, suggesting potential as a treatment for hair loss.

This study reports that six women developed scleroderma while taking L-tryptophan and showed improvement after stopping the supplement and/or starting corticosteroid therapy.

In this study, low-dose BPA was associated with induced prostatic hyperplasia in rats, potentially mediated by COX-2 and L-PGDS through pathways involving cell proliferation and apoptosis.

This study found that PES1CMU-defatted rice bran (DFRB) showed effective skin whitening and anti-aging properties comparable to standard treatments in cell models, suggesting its potential use in dermatocosmetics.

This study observed that repeated perm treatments decrease disulfide bonds in hair due to their conversion largely into cysteic acid, affecting the waving efficiency depending on the reduction agent used.

This study concluded that high-dose oral therapy with L-cystine, gelatin, and vitamin A significantly improved hair growth indicators in patients with diffuse hair loss, with no systemic side effects observed.

This review discusses the clinical significance of L-Lysine in treating various conditions and reports mixed findings on its effectiveness against herpes simplex virus infections, with no new experimental results presented.

This study observed a higher incidence of telogen effluvium from July to October, suggesting a summer-related effect in populations above the Tropic of Cancer, possibly influenced by ultraviolet light.

This study found that hydrophobic amino acids from egg white hydrolyzed protein and L-phenylalanine effectively penetrate deep into the human hair fiber, increasing specific contents in both virgin and bleached hair.

This study demonstrated that high doses of L-cystine and vitamin B6 effectively prevent doxorubicin-induced hair loss in mice.

This case report describes a patient with eosinophilia-myalgia syndrome, likely linked to L-tryptophan use, who developed a skin rash characterized by cutaneous mucinosis.