December 2021 in “International journal of research - granthaalayah” This report discusses a case of pilomatrixoma, an uncommon benign skin tumor, and emphasizes the importance of histopathological analysis for accurate diagnosis to avoid misdiagnosis as malignancy.
3 citations
,
June 2022 in “European journal of human genetics” This study reports the first cases of recessive KRT17-related pachyonychia congenita involving all ectodermal derivatives in seven members of two consanguineous Pakistani families.
July 2022 in “BMJ Case Reports” In this study, researchers identified and characterized three specific enzymes in root hair cells that play crucial roles in controlling root hair growth by affecting cell wall properties during expansion.
January 2019 in “Advances in stem cells and their niches” Krox20 is important for cell differentiation in the brain and hair follicles.
May 2026 in “Frontiers in Immunology” This case report documents the first use of bimekizumab as monotherapy for dissecting cellulitis of the scalp, where a 27-year-old man experienced significant symptom relief without adverse effects after failing standard treatments.
3 citations
,
January 2023 in “American journal of physiology. Cell physiology” This editorial reviews the roles and therapeutic potential of inward rectifying K+ channels in various physiological processes, highlighting their importance in health and disease but provides no new experimental results.
December 2025 in “International Journal of Research in Dermatology” This study observed that keratosis pilaris is the most prevalent follicular keratotic disease, especially in adolescent and young adult females, and emphasized the key role of dermoscopy and histopathology in distinguishing it from other similar disorders and aiding in diagnosis.
This study found that glycerol most significantly influenced the spreadability and initial viscosity of a saw palmetto anti-hair loss cream, while PEG 400 predominantly affected viscosity changes over time.
7 citations
,
January 1990 June 2026 in “Skin Appendage Disorders” This study suggests that pili annulati is likely more common than traditionally thought, highlighting the importance of recognizing its characteristic clinical and trichoscopic features for accurate diagnosis.
April 2021 in “Cermin Dunia Kedokteran” This report describes two cases of tinea capitis in young siblings, with cultures showing M. canis and Rhodotorulla, and notes improvement after treatment with ketoconazole lotion and shampoo for two months.
1 citations
,
May 2024 in “Pediatric Blood & Cancer” In this case study, a transition to the MEK inhibitor trametinib successfully stabilized disease and reduced toxicity in a patient with refractory kaposiform lymphangiomatosis after prolonged sirolimus and steroid treatment.
2 citations
,
January 2002 in “Zhiwu Yanjiu” Capitate trichomes have more endoplasmic reticulum and vacuoles, while peltate trichomes have more plastids and larger subcuticular spaces.
1 citations
,
August 2023 in “Clinical, Cosmetic and Investigational Dermatology” In this study, researchers observed that a hidden scalp condition could contribute to acne keloidalis nuchae and potentially other primary cicatricial alopecias, impacting their diagnosis and treatment.
80 citations
,
June 2002 in “Molecular Biology of the Cell” This study found that type II keratins in proliferating epithelial tissues are phosphorylated at a conserved motif during mitosis and stress, impacting keratin solubilization and reorganization.
This study details the presence of two types of cysts in rhino mouse skin, with utricles derived from hair canals and deeper cysts from hair root sheath epithelium.
January 2017 in “대한미용학회지” This study observed that hair follicle cuticular cells undergoing keratinization were significantly thicker than those in a normal hair shaft, due to incomplete loss of cytosol.
This review discusses the cornification process of epidermal keratinocytes in forming the skin barrier and reports no new results; it emphasizes the importance for diagnosis and treatment of skin disorders.
Saw palmetto cream for hair loss works better with glycerol and sorbitol.
2 citations
,
January 1989 in “The Nishinihon Journal of Dermatology” This study found that seborrheic keratosis lesions contain high levels of hair sheath keratin, suggesting they may originate from the upper hair follicle.
February 2026 in “American Journal of Case Reports” This case report describes a 26-year-old woman with an uncommon presentation of varicella zoster virus interstitial keratitis misdiagnosed as corneal intraepithelial neoplasia; the correct identification using diagnostic tools such as AS-OCT prevented unnecessary surgical interventions and allowed for effective antiviral treatment.
May 2006 in “The Journal of Cell Biology” In this study, researchers at Johns Hopkins University found that Keratin 17 plays a signaling role in cell growth during a wound response by aiding mTOR pathway activation, beyond its structural functions.
February 2025 in “International Journal of Advanced Research” This study highlights Ayurveda's holistic approach to managing hair loss, known as Khalitya, through lifestyle changes, purification therapies, and targeted medications, addressing the condition's association with modern sedentary lifestyles and poor dietary habits.
December 2016 in “Indonesian Journal of Tropical and Infectious Disease/Indonesian Journal of Tropical an Infectious Disease” In this case report, a two-year-old girl with kerion type of tinea capitis successfully achieved clinical and mycologic cure with double pulse dose terbinafine and 2% ketoconazole shampoo over two months, with excellent tolerability and no side effects.
4 citations
,
April 1989 in “The Journal of Dermatology” This study observed in mouse skin that trichohyalin granules in hair follicles transform into filamentous structures as inner root sheath cells differentiate and cornify.
87 citations
,
July 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that beard hair medulla cells express an unexpected range of keratins, showing variability and promiscuous behavior in keratin interactions distinct from other hair follicle cells.
December 2010 in “HAL (Le Centre pour la Communication Scientifique Directe)” This study found that the corneal epithelium differentiation program can proceed independently of lens formation, suggesting the corneal program is the default in eye development.
11 citations
,
January 1981 in “Cells Tissues Organs” This article describes the structure and components of hair cuticle cells and their intercellular junctions but reports no new clinical results.
April 2023 in “Journal of Investigative Dermatology” This study found that KROX20 is crucial for hair follicle development and epidermal homeostasis, as its deletion in skin epithelial cells led to hair loss and increased epidermal thickness.
1 citations
,
January 2015 in “Journal of clinical case reports” This case report describes two siblings with Keratosis Follicularis Spinulosa Decalvans, illustrating its manifestations in a 9-year-old boy and a 5-year-old girl.