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Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Ruxolitinib effectively regrows hair in most patients with severe hair loss.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Fat cells in the skin help start healing and form important repair cells after injury.

Scientists created stem cells that can grow hair and skin.

Mice without the Sept4/ARTS gene heal wounds better due to more stem cells that don't die easily.

A patient with alopecia areata regrew hair after taking tofacitinib and showed changes in certain blood and skin markers.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

Nitric oxide gel helps heal skin burns faster by improving skin growth, hair regrowth, and blood vessel formation.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Lymphatic vessels are essential for hair follicle growth and skin regeneration.

Researchers found a way to create cells from stem cells that act like human cells important for hair growth and could be used for hair regeneration treatments.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

Regenerative therapies show promise for treating vitiligo and alopecia areata.

Erbium glass laser treatment may help with skin remodeling, reduce inflammation, and improve skin cell maturation.

Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.

Poor maternal nutrition can lead to fewer wool follicles in Chinese Merino sheep.

Non-immune factors play a significant role in alopecia areata.

Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.

Chemotherapy can cause significant hair thinning and changes in hair texture, while tamoxifen has a smaller effect.

Vitamin D and calcium are important for quick and effective skin wound healing.

The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.

The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.