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The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.

FGF5 spliceosomes inhibit rabbit hair growth by affecting gene expression.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

A gene mutation worsens skin irritation in mice due to a lack of certain fats.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.

Skin organoids are a promising new model for studying human skin development and testing treatments.

lncRNAs may regulate hair follicle development in Hu sheep.

The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.

Skin cell-derived vesicles can help heal skin injuries effectively.

Researchers created a model to understand heart aging, highlighting the role of microRNAs and identifying key genes and pathways involved.

Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.

Removing Sprouty genes in mice causes various hormone-related issues but does not increase cancer risk by one year of age.

Immune cells are essential for early hair and skin development and healing.

Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Special cell particles from macrophages can help hair grow.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Metformin, a diabetes drug, may help prevent and treat various cancers, but more research is needed.

Keeping β-catenin levels high in mammary cells disrupts their development and branching.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

The research found genes and miRNAs that may control hair growth in Forest Musk Deer.

Bexxar is highly effective as a first treatment for non-Hodgkin's lymphoma, with most patients alive and many in remission after eight years.

The Kras mutation changes normal cell signals, leading to disrupted tissue structure and potential cancer.

A specific mutation known for causing cancer is also found to cause a skin condition in a young girl.