7 citations
,
January 2015 in “Biological & Pharmaceutical Bulletin” This study found that a 16-week dermal application of rice bran extract significantly increased hair density and diameter in male androgenic alopecia patients without causing adverse reactions.
51 citations
,
October 2024 in “Pharmaceutics” This review highlights the potential of permeation enhancers to improve the delivery of active ingredients across the skin, optimizing therapeutic outcomes despite challenges posed by individual variability and environmental factors, according to the authors' analysis of current understanding and applications in skincare and transdermal therapies.
21 citations
,
January 2022 in “Pharmaceutics” This systematic review investigated colchicine as a potential treatment for various skin conditions, finding that most studies reported generally positive clinical outcomes when used alone or with other drugs, despite some variability in results.
4 citations
,
March 2022 in “Pharmaceutics” This review explores regenerative treatment options for non-scarring alopecia, with a focus on the potential of mesenchymal stem cells for hair regrowth, but it reports no new clinical results.
July 2026 in “Pharmacological Reports” In this pilot study, topical latanoprost acid was observed to increase hair count and improve hair follicle structure in women with androgenetic alopecia, with no serious adverse events, suggesting potential for further investigation to confirm its efficacy and safety.
19 citations
,
October 2017 in “European Journal of Pharmaceutics and Biopharmaceutics” This study found that the MXD/HP-β-CD GEL formulation promoted greater hair growth and improved gene expression related to hair growth in male rats compared to MXD solution or control groups.
5 citations
,
January 2011 in “Korean Journal of Pharmacognosy” This study found that Cornus officinalis fermented with Lactobacillus rhamnosus enhanced hair regrowth in mice, outperforming a minoxidil control.
2 citations
,
December 2017 in “Bangladesh Journal of Pharmacology” In this study, N. sativa oil and decoction significantly protected against chemotherapy-induced alopecia in albino rats.
June 2023 in “BMC Pharmacology and Toxicology” This study is investigating the efficacy and safety of proxalutamide, an androgen receptor antagonist, in treating severe or critically ill patients with COVID-19, aiming to provide new insights into potential therapeutic options. Results are not reported yet.
219 citations
,
March 2004 in “Journal of The American Academy of Dermatology” In this 48-week trial, 5% topical minoxidil was more effective than both 2% minoxidil and placebo in promoting hair growth in women with female pattern hair loss, with notable improvements in nonvellus hair count and hair growth assessments.
February 2024 in “Asian Journal of Pharmaceutical and Clinical Research” This study found that human platelet lysate, prepared from expired platelet concentrate, maintained stable growth factor levels for up to six months and improved healing in second-degree burn wounds compared to standard silver sulfadiazine treatment at three weeks.
July 2021 in “Journal of reports in pharmaceutical sciences” This study evaluated a new aqueous-based nanosuspension of minoxidil for treating androgenetic alopecia and reported it was as effective as the commercial product but had better safety and tolerability, potentially improving patient compliance.
October 2023 in “Apollo medicine” This review highlights that the epidermis acts as an endocrine organ, synthesizing and responding to hormones such as corticosteroids and Vitamin D, impacting processes like hair growth and immune response, and participating in regulating endocrine balance.
March 2025 in “HAL (Le Centre pour la Communication Scientifique Directe)” This thesis investigates the underlying mechanisms and treatment options for androgenetic alopecia, highlighting the molecular roles of androgens and genetic predispositions, and evaluates current and emerging therapies, such as PROTACs and Janus Kinase inhibitors, to enhance patient management.
119 citations
,
June 2005 in “Journal of Molecular and Cellular Cardiology” This article reviews the therapeutic potential of potassium channel openers for various conditions related to metabolic distress but does not report new clinical results; it emphasizes the need for further research.
81 citations
,
June 2010 in “Journal of Dermatological Treatment” This review discusses recent advancements in hair rejuvenation strategies and assesses the potential of herbal drugs as safer alternatives, but reports no new clinical results.
39 citations
,
June 2013 in “Journal of Cosmetic Dermatology” This study found that combining herbal extracts with PRP increased human dermal papilla cell proliferation via ERK and Akt protein regulation, suggesting its potential for developing hair growth therapies.
34 citations
,
July 2011 in “Journal of Dermatological Treatment” This study found that a combination of 5% hexane extract of Curcuma aeruginosa and 5% minoxidil slowed hair loss and increased hair growth in men with androgenetic alopecia.
23 citations
,
January 2022 in “Biomaterials Science” Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.
2 citations
,
February 1981 in “Journal of the Royal Society of Medicine” A three-year-old girl survived a rare serious infection caused by BCG vaccination, which improved after treatment with a leprosy drug.
1 citations
,
July 2025 in “SKIN The Journal of Cutaneous Medicine” In this study, ritlecitinib 50-mg showed clinically meaningful efficacy, with improvements in the Severity of Alopecia Tool score observed in patients with alopecia areata over a 3-year period, demonstrating long-term benefit in both clinician- and patient-reported outcomes.
266 citations
,
November 2013 in “European Journal of Epidemiology” This article outlines the rationale and design of the Rotterdam Study, summarizes its major findings, and updates its objectives and methods; it reports no new research results.
263 citations
,
February 2013 in “Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology” This review discusses nanoparticle-based topical delivery systems for treating skin diseases and presents no new clinical findings; it emphasizes natural polymer-based nanoparticles and future applications like targeted drug delivery.
212 citations
,
September 2008 in “Journal of The American Academy of Dermatology” This review discusses the various treatment options for male and female pattern hair loss and provides no new clinical results; the authors outline the most effective strategies based on existing evidence.
30 citations
,
October 2014 in “Journal of The American Academy of Dermatology” This article reviews current treatment options for acne, hirsutism, and androgenetic alopecia in women with PCOS, recommending individualized and multidisciplinary approaches, but reports no new clinical results.
26 citations
,
December 2019 in “Neurobiology of Stress” This review discusses adverse effects of 5 alpha-reductase inhibitors, particularly persistent side effects such as post-finasteride syndrome, and highlights the need for further investigation.
25 citations
,
July 2020 in “Journal of cosmetic dermatology” In this study, the authors reported that while deoxycholic acid effectively reduces submental fat, it can cause adverse effects such as edema, numbness, and skin necrosis, making knowledge of possible complications essential for clinicians.
15 citations
,
November 2017 in “Drug Delivery and Translational Research” This study found that co-applying Curcuma aeruginosa extract or essential oil with minoxidil significantly increased minoxidil's skin penetration in an ex vivo setting, suggesting an improved topical treatment strategy for androgenic alopecia with greater efficacy and the potential for lower minoxidil doses.
9 citations
,
March 2019 in “European Journal of Sport Science” This article discusses laboratory and physical markers that may help detect androgenic anabolic steroid abuse in athletes and reports no new primary research results.
4 citations
,
December 2013 in “International Journal of Dermatology” This correspondence discusses nasal sporotrichosis in children and does not report any clinical results.