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The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

The nanofibers with two growth factors improved wound healing by supporting structure, preventing infection, and aiding tissue growth.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

PGD2 stops hair growth and is higher in bald men with AGA.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Androgens can cause hair growth in some areas and hair loss on the scalp.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Memory regulatory T cells need IL-7, not IL-2, to stay in peripheral tissues.