58 citations
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June 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that Atlantic croaker nuclear androgen receptors AR1 and AR2 have different binding affinities for androgens, suggesting that they may mediate distinct physiological actions in teleosts.
September 2002 in “Research Repository (Kingston University London)” This review discusses strategies for treating hormone-dependent prostate diseases and synthesizes a range of potential 5α-reductase inhibitors, but experimental evaluation of these compounds was not completed.
6 citations
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April 2013 in “Alternative and Complementary Therapies” Raspberry ketone lacks sufficient human research to support health benefit claims and requires more rigorous studies to confirm its safety and effectiveness.
43 citations
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January 1970 in “Acta Medica Scandinavica” This study found that obese patients experienced similar weight loss on a very low-calorie diet and total fast, but the diet was associated with fewer complications.
January 2015 in “Springer eBooks” Some alternative treatments may help with hair loss, but more evidence is needed to confirm their effectiveness.
October 2020 in “International Journal of Medical Arts (Print)” This study found that for anterior cervical discectomy fusion in patients with degenerative cervical disc disease, the PEEK cage resulted in greater pain reduction, while the dynamic cervical implant maintained a slightly better range of motion.
39 citations
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March 2008 in “Growth hormone & IGF research” Raspberry ketone may help grow hair and improve skin elasticity.
In this study, researchers found that while applying a lotion containing Lactiplantibacillus plantarum subsp. plantarum N793 did not improve hair density overall compared to placebo, it was effective in improving hair density among individuals with relatively mild hair thinning.
93 citations
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February 2008 in “Atmospheric environment” In this study, researchers found that human scalp hair, particularly when unwashed, can significantly react with ozone, reducing personal ozone exposure and increasing exposure to volatile reaction products.
March 2022 in “International Journal of Current Science Research and Review” This article describes subclinical ketosis in pregnant cows and associates it with several metabolic changes and clinical signs, reporting decreased levels of hemoglobin and glucose and increased ketone bodies.
This review discusses potential cosmeceutical treatments for hair loss, including ingredients like procyanidins and isoflavones, but does not present new clinical outcomes; the authors highlight the promise of further research.
March 2021 in “Research Square (Research Square)” This study analyzed the structure and dynamics of ketoconazole, revealing how its molecular characteristics, such as spin-lattice relaxation time and chemical shift anisotropy, are influenced by π-π stacking interactions and different carbon site environments.
40 citations
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August 2018 in “Skin appendage disorders” This review examines complementary and alternative medicine for alopecia and finds limited support from robust clinical trials, highlighting the need for standardized studies to evaluate efficacy and safety.
11 citations
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April 2021 in “Advanced synthesis & catalysis” This study reports that the dye peri-xanthenoxanthene (PXX) can act as an efficient photocatalyst for various radical reactions, including complex dual catalytic processes and the synthesis of an investigational drug intermediate.
May 2010 in “Europe PMC (PubMed Central)” This chapter discusses the synthesis and analysis of near-infrared fluorescent activity-based probes for imaging cysteine protease activity, reporting potential benefits for disease diagnosis but noting challenges in imaging specific locations with high cathepsin activity.
December 2008 in “Enzyme and Microbial Technology” New patents include innovations in skin and hair care, disease treatment, plant stress tolerance, and protein purification.
July 2024 in “Applied Sciences” This study found that bimatoprost was significantly more effective than sweet almond oil in increasing eyebrow hair density and length in young women over a 5-week period.
April 2022 in “Journal of applied science and environmental management” This study found that Aframomum melegueta seed extract improved wound healing in albino rats, with treated groups showing smaller wound sizes and formation of new tissues compared to controls.
7 citations
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October 2024 in “AAPS PharmSciTech” This study developed a caffeine-loaded solid lipid nanoparticle gel, observing significant reduction in subcutaneous fat tissue thickness in histological tests compared to an untreated group, suggesting it could effectively treat cellulite as a promising nanocosmeceutical gel.
1 citations
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January 2024 in “NPJ breast cancer” This study, using modified Delphi panels, provided consensus recommendations for managing alpelisib-induced hyperglycemia and rash, advising prophylactic metformin starting for certain risk groups and the use of nonsedating H1 antihistamines and topical steroids for initial rash management.
November 2022 in “CARDIOMETRY” This article discusses the potential benefits of GcMAF and oral MAF, developed by "Saisei Mirai", for cancer and other conditions, but reports no new clinical results.
10 citations
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September 2013 in “Nutrition” In this animal study, the ketogenic diet was associated with more severe biotin deficiency in biotin-deficient mice, suggesting that biotin supplementation is important when following this diet.
1 citations
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August 2024 in “Journal of Pharmacy & Pharmaceutical Sciences” This study found that forming inclusion complexes of DPCP with HPβCD using the 3D ground mixture method enhances its anti-inflammatory activity at lower doses compared to complexes with β-CD.
4 citations
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May 2024 in “Rapid Communications in Mass Spectrometry” This study demonstrated that GP derivatization improves mass spectral analysis of spironolactone and its metabolites by reducing in-source fragmentation and enhancing signal clarity, laying the groundwork for future advancements in reaction optimization and quantitative assay development.
June 2021 in “Research Square (Research Square)” This study reports that melatonin influences gene expression related to cashmere growth cycles in Inner Mongolian cashmere goats, potentially aiding in understanding and enhancing cashmere yield through molecular regulation.
August 2019 in “Placenta” This article reviews the use of spironolactone in dermatology for conditions like female acne, suggesting it may reduce antibiotic and isotretinoin use, and stresses its long-term safety.
68 citations
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April 2002 in “Journal of Human Nutrition and Dietetics” This study found that although diabetic patients undergoing a very low calorie diet experienced faster weight loss initially, those on a conventional diet and exercise plan maintained weight loss more effectively over five years.
1 citations
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December 2019 in “Canadian journal of ophthalmology” This study presents a case of a pubertal girl with type 1 diabetes who developed proliferative diabetic retinopathy shortly after diagnosis, suggesting the need for earlier screening in high-risk groups.
August 2023 in “The Indonesian Biomedical Journal” This study on UVB-exposed mice found that topical application of 10% Rosmarinus officinalis essential oil significantly increased hair length and follicle diameter, attributed potentially to its antioxidant compounds.
19 citations
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May 1991 in “Journal of Chromatography B: Biomedical Sciences and Applications” This study developed and validated an HPLC method for detecting a novel 5α-reductase inhibitor in human plasma, supporting its pharmacokinetic evaluation at low doses.