This study details the presence of two types of cysts in rhino mouse skin, with utricles derived from hair canals and deeper cysts from hair root sheath epithelium.
January 1953 in “The Lancet” Cortisone may help hair regrow by altering the local environment, with regrowth starting 3-4 weeks after treatment, but its use is not widely recommended.
April 1906 in “The American Journal of the Medical Sciences” Keratosis Pilaris Atrophicans causes skin scarring and might be treated with a new synthetic retinoid.
52 citations
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April 2012 in “Journal of Investigative Dermatology” This study found that KRTAP2 proteins predominantly express in the hair shaft cortex of humans, interact with hair keratins, and play crucial roles in hair shaft keratinization.
14 citations
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April 2014 in “International Journal of Cosmetic Science” This article discusses the multifactorial etiopathogenesis of acne vulgaris, highlighting the roles of sebum production, keratosis, bacterial development, and inflammatory mediators, but reports no new clinical results.
4 citations
,
December 2022 in “International Journal of Molecular Sciences” This review discusses the role of zinc and its transporters in skin health and disorders, providing an overview without presenting new clinical results.
2 citations
,
January 2011 in “Elsevier eBooks” This book reviews the various types of acne and acneiform conditions, as well as their treatment options, with expert insights from multiple fields.
55 citations
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October 1992 in “Archives of Dermatology” In this study, researchers observed that loose anagen hair syndrome is an autosomal dominant disorder characterized by abnormal hair follicle structure and premature keratinization, possibly due to signaling and desmosomal component disturbances.
88 citations
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July 2001 in “British journal of dermatology/British journal of dermatology, Supplement” This study reported that antimicrobial and topical retinoid therapies led to significant changes in the lipid profiles of sebaceous follicular infundibulum, with increased triglycerides and ceramide subfractions observed.
39 citations
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June 2012 in “Journal of Structural Biology” Disulfide bonds are crucial for hair structure during keratinization.
34 citations
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October 2024 in “Clinical Cosmetic and Investigational Dermatology” This review discusses azelaic acid's mechanisms and uses in dermatology, noting its effectiveness in treating conditions like rosacea, acne, and melasma, but reports no new clinical results.
19 citations
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April 2019 in “Journal of the European Academy of Dermatology and Venereology” This study found that acne lesion formation involves early hyperkeratinization and inflammation around hair follicles, creating a self-sustaining cycle that may progressively worsen acne.
18 citations
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March 2009 in “Experimental Dermatology” This study suggests that pilomatricoma can differentiate towards various hair follicle structures, including hair matrix, hair cortex, follicular infundibulum, outer root sheath, and hair bulge.
13 citations
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January 2012 in “Dermatology” This case study and literature review describe eruptive vellus hair cysts as uncommon, potentially inherited or acquired lesions, associated with other skin conditions, and challenging to treat despite being benign.
12 citations
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February 1997 in “British Journal of Dermatology” This study found that 5α–reductase activity is higher in infrainfundibular keratinocytes compared to interfollicular epidermal keratinocytes, suggesting a potential role in acne-related follicular changes.
9 citations
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July 2016 in “The Journal of Dermatology” This letter to the editor discusses an observed case of hair repigmentation linked with etretinate therapy but reports no new research findings.
6 citations
,
December 1990 in “PubMed” This study examined the expression patterns of various cytokeratins in the outer root sheath of human anagen hair follicles, noting distinct differentiation patterns and localization of keratin markers.
5 citations
,
August 2000 in “Archives of Pathology & Laboratory Medicine” This case report describes an 89-year-old woman with a recurrent benign proliferating trichilemmal tumor on her back, highlighting its misdiagnosis as a sebaceous cyst and successful excision with free margins.
3 citations
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January 2025 in “Discovery Medicine” This study found that glycolic acid treatment reduced oxidative stress and inflammation in UV-induced skin photoaging in rats, promoting collagen recovery and reducing photoaging signs, potentially by inhibiting the PI3K/Akt and NF-κB pathways.
2 citations
,
December 2019 in “Colombia medica” This article discusses promising therapies for perifolliculitis capitis abscedens et suffodiens and reports no new clinical results; management includes isotretinoin and other medications targeting its underlying causes.
2 citations
,
June 2012 in “American Journal of Dermatopathology” This case study describes a rare cutaneous follicular hybrid cyst intimately associated with syringocystadenoma papilliferum, proposing a potential relationship with the infrainfundibulum based on keratin expression.
1 citations
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July 2018 in “Journal of dermatology & cosmetology” This case report describes a treatment approach for frontal and temporal alopecia using oral dutasteride, minoxidil lotion, and triamcinolone injections, with hyaluronic acid successfully treating injection site atrophy.
1 citations
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January 1995 in “Skin Cancer” This study suggests that immunohistochemistry of keratin and involucrin expression can aid in distinguishing malignant trichilemmoma from other tumors previously diagnosed as such.
January 2026 in “International Journal of Research and Innovation in Applied Science” This case report details a rare instance of malignant proliferating trichilemmal tumour in a 60-year-old male, emphasizing the significance of histochemical and immunohistochemical markers for accurate diagnosis and differentiation from squamous cell carcinoma.
July 2025 in “Journal of Investigative Dermatology” Acne involves increased lipid production and inflammation, affecting skin cell behavior and treatment resistance.
August 2023 in “Journal of the European Academy of Dermatology and Venereology” This case report describes an unusual nail tumor termed "onycholemmal horn" in a 77-year-old woman, highlighting its distinct histopathological features and the importance of excisional biopsy for accurate diagnosis.
June 2023 in “World Journal of Biology Pharmacy and Health Sciences” This review outlines the complex factors involved in acne pathogenesis—including hormonal, genetic, and environmental influences—and describes current comprehensive management strategies, emphasizing both topical and systemic therapies, while also highlighting emerging treatment options and the significant psychological impact of acne.
November 2022 in “JAAD case reports” This report diagnosed a 68-year-old man with comedonal folliculotropic mycosis fungoides based on clinical and histopathological findings, and found pegylated interferon alpha-2a with isotretinoin beneficial in reducing skin lesions.
January 2017 in “Padua@research (University of Padova)” This research explored the potential of mesenchymal stem cells in developing therapies for tendon, muscle, and skin injuries in horses and sheep, indicating possible benefits in cellular regeneration and repair.
January 2008 in “Pratique médicale & chirurgicale de l'animal de compagnie” This review discusses the controversial non-inflammatory alopecia known as alopecia X, highlighting its unknown etiology and the variable effectiveness of various proposed treatments, but reports no new results.