An Updated Review on Acne
June 2023
in “
World Journal of Biology Pharmacy and Health Sciences
”
New to Tretinoin? There is a guide in the encyclopedia. Read the guide → acne comedones papules pustules nodules cysts hormonal imbalances sebum production follicular keratinization Propionibacterium acnes retinoids benzoyl peroxide antibiotics oral antibiotics hormonal agents isotretinoin laser therapy light-based therapies photodynamic therapy probiotics botanical extracts P. acnes Accutane Retin-A Benzac Proactiv
Studysummary This review outlines the complex factors involved in acne pathogenesis—including hormonal, genetic, and environmental influences—and describes current comprehensive management strategies, emphasizing both topical and systemic therapies, while also highlighting emerging treatment options and the significant psychological impact of acne. Our plain-language summary of this paper — not a Tressless recommendation.
Acne is a chronic inflammatory skin disorder that affects individuals of all ages, particularly adolescents, and is characterized by comedones, papules, pustules, and in severe cases, nodules and cysts. Its pathogenesis involves hormonal imbalances, increased sebum production, abnormal follicular keratinization, and the colonization of Propionibacterium acnes. Various factors such as genetic susceptibility, diet, and environmental influences contribute to acne development and exacerbation. Management strategies include topical agents like retinoids, benzoyl peroxide, and antibiotics, and systemic therapies like oral antibiotics, hormonal agents, and isotretinoin. Emerging therapies include laser and light-based therapies, photodynamic therapy, and the use of probiotics and botanical extracts. The psychological impact of acne, affecting self-esteem, body image, and social interactions, emphasizes the need for a holistic approach to patient care.
