July 1997 in “The Lancet” Finasteride increased hair count and regrowth in men with hair loss but also caused more sexual side effects than placebo.
173 citations,
January 2014 in “Nature Cell Biology” Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
116 citations,
August 2010 in “Nature” Scientists turned rat thymus cells into stem cells that can help repair skin and hair.
72 citations,
February 2011 in “American Journal of Biological Anthropology” The conclusion is that recognizing hair growth cycles can improve the precision of dietary and health assessments from hair analysis.
64 citations,
May 2019 in “Materials Science and Engineering: C” Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.
51 citations,
November 2013 in “Drug Discovery Today” Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
41 citations,
March 2007 in “Journal of dermatological science” Taking L-cystine and vitamin B6 can prevent hair loss caused by smoke in mice.
36 citations,
August 2018 in “Dermatologic Clinics” Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.
34 citations,
September 2009 in “International Journal of Dermatology” Using anabolic-androgenic steroids can cause skin problems like acne and hair loss in athletes.
30 citations,
July 2017 in “BioEssays” Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
27 citations,
September 2012 in “Dermatologic Clinics” The document concludes that using specific tools and tests is essential for identifying the cause of hair loss and deciding on the right treatment.
10 citations,
April 2016 in “Research and reports in transdermal drug delivery” Transfollicular drug delivery is promising but needs more research to improve and understand it better.
10 citations,
February 2008 in “Photochemistry and photobiology” Vitamin D receptor can control the hairless gene linked to hair loss even without vitamin D.
9 citations,
April 2019 in “Journal of structural biology” Hair's internal fibers are arranged in a pattern that doesn't let much water in, and treatments like oils and heat change how much water hair can absorb.
6 citations,
June 2011 in “Pharmacognosy Journal” Many products for hair re-growth exist, but a perfect treatment without side effects has not yet been found.
3 citations,
July 1997 in “The Lancet” Finasteride may increase hair growth and prevent baldness in men, but can cause sexual side effects.
2 citations,
August 2020 in “Clinical, Cosmetic and Investigational Dermatology” The hair-growth formula with L-cystine helps protect and grow hair cells.
1 citations,
April 2010 in “Expert Review of Dermatology” The document concludes that early diagnosis and treatment are crucial for managing rare hair loss disorders and that more research is needed to improve treatment strategies.
June 2019 in “The Egyptian Journal of Histology” Hyaluronic acid injections improve skin thickness and quality, protecting against aging in rats.
October 2018 in “InTech eBooks” The gene Foxn1 is important for hair growth, and understanding it may lead to new alopecia treatments.
June 2008 in “Springer eBooks” The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."
262 citations,
May 2017 in “Nanomedicine” New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.
185 citations,
February 2018 in “Journal of Investigative Dermatology” Melatonin may benefit skin health and could be a promising treatment in dermatology.
150 citations,
October 2010 in “The American Journal of Pathology” The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
132 citations,
January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
130 citations,
August 2020 in “Drug Design Development and Therapy” Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
96 citations,
October 2000 in “The FASEB Journal” The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.
66 citations,
May 2021 in “Science Advances” Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
65 citations,
January 2018 in “Nature Reviews Endocrinology” Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
65 citations,
November 2012 in “Tissue Engineering Part B-reviews” Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.